Results 11 to 20 of about 19,636,220 (230)
The phospholipase C isozymes and their regulation. [PDF]
Sub-cellular biochemistry, 2012 The physiological effects of many extracellular neurotransmitters, hormones, growth factors, and other stimuli are mediated by receptor-promoted activation of phospholipase C (PLC) and consequential activation of inositol lipid signaling pathways. These signaling responses include the classically described conversion of phosphatidylinositol(4,5)P(2) to
Aurélie Gresset
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Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant. [PDF]
PLoS ONE, 2012 BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one ...
Fabian Runkel +7 more
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Zhongguo youzhi, 2022 为了提高脱胶效率，以冷榨菜籽原油为原料，磷脂含量为指标，采用磷脂酶Lecitase Ultra和磷脂酶C复合酶法对冷榨菜籽油进行脱胶。采用单因素试验考察磷脂酶Lecitase Ultra反应时间、磷脂酶C反应时间、加水量、磷脂酶Lecitase Ultra添加量、磷脂酶C添加量、柠檬酸溶液添加量对脱胶油磷脂含量的影响，并通过响应面法优化脱胶条件。对优化的脱胶条件下所得到的脱胶油的理化指标进行了检测，并与国标一级压榨菜籽油进行了比较。结果表明：磷脂酶Lecitase ...
马云睿1，周力1，高盼1,2，胡传荣1,2，罗质1,2，何东平1,2MA Yunrui1, ZHOU Li1, GAO Pan1,2, HU Chuanrong1,2, LUO Zhi1,2, HE Dongping1,2
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Liang you shipin ke-ji, 2021 The enzymatic degumming process of crude corn oil using phospholipase C from Thielavia terrestris was studied.The key factors affecting the enzymatic degumming efficiency of crude corn oil,including enzyme dosage, volume ratio of NaOH to citric acid ...
HU Ting-ting +4 more
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AIMS Biophysics, 2023 Different signal transduction pathways contribute to the differentiation and metabolic activities of osteoblasts, with special regard to the calcium-related pathway of phosphoinositide specific phospholipase C (PLC) enzyme family.
Matteo Corradini +5 more
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PTEN regulates phospholipase D and phospholipase C [PDF]
Human Molecular Genetics, 2007 PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Charis Eng +3 more
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Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain
Molecules, 2022 Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo +8 more
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Regulation of phosphoinositide-specific phospholipase C.
Annual Review of Biochemistry, 2001 Eleven distinct isoforms of phosphoinositide-specific phospholipase C (PLC), which are grouped into four subfamilies (beta, gamma, delta, and epsilon), have been identified in mammals.
S. Rhee
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Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice
Scientific Reports, 2018 Sperm entry in mammalian oocytes triggers intracellular Ca2+ oscillations that initiate resumption of the meiotic cell cycle and subsequent activations.
K. Nozawa +4 more
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Regulation and physiological functions of mammalian phospholipase C.
Journal of Biochemistry (Tokyo), 2017 Phospholipase C (PLC) is a key enzyme in phosphoinositide metabolism. PLC hydrolyses phosphatidylinositol 4,5-bis-phosphate to generate two second messengers, inositol 1,4,5-trisphosphate and diacylglycerol, that generate diverse cellular responses.
Yoshikazu Nakamura, K. Fukami
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