Results 31 to 40 of about 308,555 (173)

Membrane Lipid Derivatives: Roles of Arachidonic Acid and Its Metabolites in Pancreatic Physiology and Pathophysiology

open access: yesMolecules, 2023
One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family of enzymes termed phospholipases: phospholipase A2 ...
Cándido Ortiz-Placín   +3 more
doaj   +1 more source

Inhibition of Phospholipase D by Amphiphysins [PDF]

open access: yesJournal of Biological Chemistry, 2000
Two distinct proteins inhibiting phospholipase D (PLD) activity in rat brain cytosol were previously purified and identified as synaptojanin and AP180, which are specific to nerve terminals and associate with the clathrin coat. Two additional PLD-inhibitory proteins have now been purified and identified as the amphiphysins I and II, which forms a ...
Michael A. Frohman   +5 more
openaire   +3 more sources

Switching the substrate specificity of lysoplasmalogen‐specific phospholipase D

open access: yesFEBS Open Bio, 2021
Lysoplasmalogen‐specific phospholipase D (LyPls‐PLD) catalyzes reactions in a manner similar to those catalyzed by glycerophosphodiester phosphodiesterase (GDPD) and other well‐known PLDs.
Takayuki Oyama   +2 more
doaj   +1 more source

Regulation of Phospholipase D in HL60 Cells [PDF]

open access: yesJournal of Biological Chemistry, 1995
Phospholipase D (PLD) activity that was stimulated by guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) was detected in cytosol and membranes of HL60 cells. GTP gamma S-stimulated PLD activity was detected in the membranes when exogenous labeled phosphatidylcholine was used in the presence of phosphatidylethanolamine and phosphatidylinositol 4,5 ...
Annette H. Ross   +5 more
openaire   +2 more sources

The Italian bondage and reinforcement numbers of digraphs [PDF]

open access: yesarXiv, 2020
An \textit{Italian dominating function} on a digraph $D$ with vertex set $V(D)$ is defined as a function $f : V(D) \rightarrow \{0, 1, 2\}$ such that every vertex $v \in V(D)$ with $f(v) = 0$ has at least two in-neighbors assigned $1$ under $f$ or one in-neighbor $w$ with $f(w) = 2$.
arxiv  

Nuclear inositides

open access: yesEuropean Journal of Histochemistry, 2009
DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
N Divecha   +4 more
doaj   +1 more source

The first crystal structure of a phospholipase D [PDF]

open access: yesStructure, 2000
The phospholipase D (PLD) superfamily includes enzymes that are involved in phospholipid metabolism, nucleases, toxins and virus envelope proteins of unknown function. PLD hydrolyzes the terminal phosphodiester bond of phospholipids to phosphatidic acid and a hydrophilic constituent.
Leiros I   +4 more
openaire   +4 more sources

Gene Expression, Bioinformatics and Substrate Selectivity of Phospholipase D from Acinetobacter sp.

open access: yesShipin gongye ke-ji
Microbial phospholipase D (PLD) showed a more competent potential for phospholipids production due to its higher catalytic activity and broader substrate specificity. In this study, the PLD from Acinetobacter sp.
Siyi WU   +7 more
doaj   +1 more source

Early LPS-induced ERK activation in retinal pigment epithelium cells is dependent on PIP2-PLC

open access: yesData in Brief, 2016
This article presents additional data regarding the study “The phospholipase D pathway mediates the inflammatory response of the retinal pigment epithelium” [1]. The new data presented here show that short exposure of RPE cells to lipopolysaccharide (LPS)
Melina V. Mateos   +3 more
doaj  

Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis

open access: yesJournal of Lipid Research, 2008
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff   +2 more
doaj  

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