Results 31 to 40 of about 308,555 (173)
One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family of enzymes termed phospholipases: phospholipase A2 ...
Cándido Ortiz-Placín+3 more
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Inhibition of Phospholipase D by Amphiphysins [PDF]
Two distinct proteins inhibiting phospholipase D (PLD) activity in rat brain cytosol were previously purified and identified as synaptojanin and AP180, which are specific to nerve terminals and associate with the clathrin coat. Two additional PLD-inhibitory proteins have now been purified and identified as the amphiphysins I and II, which forms a ...
Michael A. Frohman+5 more
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Switching the substrate specificity of lysoplasmalogen‐specific phospholipase D
Lysoplasmalogen‐specific phospholipase D (LyPls‐PLD) catalyzes reactions in a manner similar to those catalyzed by glycerophosphodiester phosphodiesterase (GDPD) and other well‐known PLDs.
Takayuki Oyama+2 more
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Regulation of Phospholipase D in HL60 Cells [PDF]
Phospholipase D (PLD) activity that was stimulated by guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) was detected in cytosol and membranes of HL60 cells. GTP gamma S-stimulated PLD activity was detected in the membranes when exogenous labeled phosphatidylcholine was used in the presence of phosphatidylethanolamine and phosphatidylinositol 4,5 ...
Annette H. Ross+5 more
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The Italian bondage and reinforcement numbers of digraphs [PDF]
An \textit{Italian dominating function} on a digraph $D$ with vertex set $V(D)$ is defined as a function $f : V(D) \rightarrow \{0, 1, 2\}$ such that every vertex $v \in V(D)$ with $f(v) = 0$ has at least two in-neighbors assigned $1$ under $f$ or one in-neighbor $w$ with $f(w) = 2$.
arxiv
DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
N Divecha+4 more
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The first crystal structure of a phospholipase D [PDF]
The phospholipase D (PLD) superfamily includes enzymes that are involved in phospholipid metabolism, nucleases, toxins and virus envelope proteins of unknown function. PLD hydrolyzes the terminal phosphodiester bond of phospholipids to phosphatidic acid and a hydrophilic constituent.
Leiros I+4 more
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Gene Expression, Bioinformatics and Substrate Selectivity of Phospholipase D from Acinetobacter sp.
Microbial phospholipase D (PLD) showed a more competent potential for phospholipids production due to its higher catalytic activity and broader substrate specificity. In this study, the PLD from Acinetobacter sp.
Siyi WU+7 more
doaj +1 more source
Early LPS-induced ERK activation in retinal pigment epithelium cells is dependent on PIP2-PLC
This article presents additional data regarding the study “The phospholipase D pathway mediates the inflammatory response of the retinal pigment epithelium” [1]. The new data presented here show that short exposure of RPE cells to lipopolysaccharide (LPS)
Melina V. Mateos+3 more
doaj
Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff+2 more
doaj