Results 171 to 180 of about 271,068 (255)

Diversité structurale des phospholipases A2 sécrétées (clonage et étude fonctionnelle de nouvelles enzymes)

, 2000
Les phospholipases A2 hydrolysent la liaison ester en position 2 des phospholipides, libérant un acide gras et un lysophospholipide. Ces enzymes jouent un rôle dans la libération d'acide arachidonique et de ses métabolites.
VALENTIN, Emmanuel, LAZDUNSKI, Michel
core  

Therapeutic Effects and Mechanisms of Fucoidan on Dyslipidemia in Obese Mice

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
In the present study, fucoidan (50 mg/kg/day) did not alter HFD‐driven weight gain or food intake, but significantly decreased serum total cholesterol (TC). Fucoidan reduced hepatic triglyceride, TC, and lipid droplets, improving hepatic lipid accumulation.
Lizhi Peng, Ruiming Li, Ruting Zheng, Ziqiong Liao, Daohuang Luo, Yuting Zeng, Jiaqi Liu, Qiaoling Kong, Jicai Lai   +8 more
wiley   +1 more source

Membrane and inhibitor interactions of intracellular phospholipases A2. [PDF]

Adv Biol Regul, 2016
Mouchlis VD, Dennis EA.
europepmc   +1 more source

Lonicerae Japonicae Flos as a Dietary Natural Product: Bioactive Constituents, Gut Health Modulation, and Therapeutic Potential in Ulcerative Colitis and Colorectal Cancer

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Bioactive constituents, mechanisms of action, and potential applications of Lonicerae Japonicae Flos as a dietary natural product for promoting gut health and managing ulcerative colitis and colorectal cancer. ABSTRACT Lonicerae Japonicae Flos (LJF), a traditional Chinese herb with applications in both medicine and nutrition, has emerged as a promising
Xiaoyu Huang, Letian Zhang, Zenghui Shi, Ni Zhu, Yifei Liu, Yanhong Zhou   +5 more
wiley   +1 more source

Phospholipases A₂ (PLA₂s) and Related Peptides from <i>Bothrops</i> Snake Venoms: History, Structure, Pharmacology, and Inhibitors. [PDF]

Biomolecules
Santos ICD, Romanazzi M, Malachias-Pires GM, Aragão AR, Filardi ETM, Melo-Dos-Santos G, Salvador LC, Cerveja MF, Rocha AM, Magalhães A, de Oliveira IS, Almeida JR, Santos-Filho NA, Pucca MB.   +13 more
europepmc   +1 more source

Antimalarial activity of basic phospholipases A₂ isolated from Paraguayan Bothrops diporus venom against Plasmodium falciparum. [PDF]

Toxicon X, 2020
Vitorino KA, Alfonso JJ, Gómez AF, Santos APA, Antunes YR, Caldeira CADS, Gómez CV, Teles CBG, Soares AM, Calderon LA.   +9 more
europepmc   +1 more source

Inhibitory activity of Murraya paniculata against myotoxic phospholipases A2

, 2010
RESUMEN: Los envenenamientos causados por serpientes del género Bothrops constituyen un problema de salud en algunos países tropicales, no solamente por la mortalidad sino por el alto porcentaje de incapacidades físicas que ocasionan. Las fosfolipasas A2
Lobo Echeverri, Tatiana, Rojano, Benjamín Alberto, Pereañez Jiménez, Jaime Andrés, Gutiérrez Sánchez, Pablo Andrés, Núñez Rangel, Vitelbina, Londoño, Mónica, Zapata Acosta, Karol   +6 more
core  

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin‐based antivenom treatment on murine plasma proteome and peptidome

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros, Alison F. A. Chaves, Mariana S. L. C. Morone, Ana T. A. Sachetto, Marcelo L. Santoro, Oliver Schilling, Solange M. T. Serrano   +6 more
wiley   +1 more source