Results 71 to 80 of about 20,305 (246)

Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]

open access: yes, 2012
Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core   +2 more sources

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu   +12 more
wiley   +1 more source

Viperidae snake venom phospholipase A2. Biochemical targets in the human blood circulatory system. Review. Part 2

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
In this review (Part 2), we describe the structural features and properties of the most studied Viperidae snake venom phospholipases A2 . Various effects of these enzymes on blood cells (erythrocytes, leukocytes and platelets), on blood coagulation and ...
L. V. Vasina   +4 more
doaj   +1 more source

METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]

open access: yes, 2000
The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core   +1 more source

Phospholipase А2 purification and characterization from venom of snake Gloydius blomhoffii brevicaudus

open access: yesБіологічні студії, 2012
Phospholipases A2 (PlA2) are the most common compounds of snake venom. Ability of the enzyme to affect cell interactions, particularly platelet aggregation, proliferation of cancer cells, processes of angiogenesis and cell differentiation, potentiates it
A. I. Zhukova   +3 more
doaj   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils [PDF]

open access: yes, 2017
Secreted phospholipases A2 (sPLA2s) are extracellular enzymes that catalyze the release of free fatty acids and lysophospholipids from membrane phospholipids and also bind to different receptors (e.g., PLA2R1 or integrins).
Borriello, Francesco   +11 more
core   +3 more sources

Phospholipase A2 and inflammation

open access: yesMolecular Medicine Today, 1995
Increased expression of secreted group II phospholipase A 2 (sPLA2) is associated with inflammation 1.This enzyme can promote a variety of potentially harmful events, which have been attributed to its catalytic activity. However, the possibility that sPLA 2 may also exert actions that do not depend on its catalytic activity has generally not been ...
Lomonte, Bruno   +2 more
openaire   +4 more sources

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller   +17 more
wiley   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

open access: yesAutism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni   +6 more
wiley   +1 more source

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