Results 51 to 60 of about 9,986 (201)

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Phospholipase A2 and Phospholipase B activities in fungi [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006
As saprophytes or disease causing microorganisms, fungi acquire nutrients from dead organic material or living host organisms. Lipids as structural components of cell membranes and storage compartments play an important role as energy-rich food source.
Gerwald A, Köhler, Audrey, Brenot, Eric, Haas-Stapleton, Nina, Agabian, Rupal, Deva, Santosh, Nigam   +5 more
openaire   +2 more sources

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Viperidae snake venom phospholipase A2. Biochemical targets in the human blood circulatory system. Review. Part 2

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
In this review (Part 2), we describe the structural features and properties of the most studied Viperidae snake venom phospholipases A2 . Various effects of these enzymes on blood cells (erythrocytes, leukocytes and platelets), on blood coagulation and ...
L. V. Vasina, L. V. Galebskaya, М. А. Galkin, М. А. Solovyeva, Yu. V. Tarasova   +4 more
doaj   +1 more source

Expression of cPLAγ mRNA and protein differs the response of PBMC from severe and non-severe asthmatics to bacterial lipopolysaccharide and house dust mite allergen

International Journal of Immunopathology and Pharmacology, 2021
Chronic inflammation in asthmatics is initiated/exacerbated by many environmental factors, such as bacterial lipopolysaccharide and allergens. Phospholipase A 2 and histone acetyltransferase/deacetylases are enzymes involved in inflammatory process ...
Ewa Pniewska-Dawidczyk, Izabela Kupryś-Lipińska, Gabriela Turek, Dorota Kacprzak, Joanna Wieczfinska, Paulina Kleniewska, Piotr Kuna, Rafal Pawliczak   +7 more
doaj   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Secreted phospholipase A2 revisited [PDF]

Journal of Biochemistry, 2011
Phospholipase A(2) (PLA(2)) catalyses the hydrolysis of the sn-2 position of glycerophospholipids to yield fatty acids and lysophospholipids. So far, more than 30 enzymes that possess PLA(2) or related activity have been identified in mammals. About one third of these enzymes belong to the secreted PLA(2) (sPLA(2)) family, which comprises low molecular
Makoto, Murakami, Yoshitaka, Taketomi, Hiroyasu, Sato, Kei, Yamamoto   +3 more
openaire   +2 more sources

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Phospholipase А2 purification and characterization from venom of snake Gloydius blomhoffii brevicaudus

Біологічні студії, 2012
Phospholipases A2 (PlA2) are the most common compounds of snake venom. Ability of the enzyme to affect cell interactions, particularly platelet aggregation, proliferation of cancer cells, processes of angiogenesis and cell differentiation, potentiates it
A. I. Zhukova, G. L. Volkov, Ye. N. Krasnobryzhaya, S. P. Gavryliuk   +3 more
doaj   +1 more source