Results 11 to 20 of about 487 (166)

Identification of a lipoxygenase inhibitor in A431 cells as a phospholipid hydroperoxide glutathione peroxidase [PDF]

FEBS Letters, 1998
An endogenous lipoxygenase inhibitor, purified from the cytosol of human epidermoid carcinoma A431 cells, was analyzed by N‐terminal microsequencing and mass spectrometric analysis. The inhibitor was purified by SDS‐PAGE, then subjected to in‐gel CNBr cleavage and trypsin digestion.
Huang, Hei-Sheng, Chen, Ching-Jiunn, Lu, Hsieng S, Chang, Wen-Chang   +3 more
openaire   +3 more sources

Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx) [PDF]

International Journal of Biological Sciences, 2010
Phospholipid hydroperoxide glutathione peroxidase (PHGPx), as a ubiquitous antioxidant enzyme in the glutathione peroxidases (GPx) family, plays multiple roles in organisms. However, there is very little information on PHGPx in goats (Capra hircus).
Li-guang SHI, Wen-juan XUN, Wen-bin YUE, Chun-xiang ZHANG, You-she REN, Qian WANG, Xiao-ying WU, Lei SHI, Ru-jie YANG, Fu-lin LEI
doaj   +1 more source

An eQTL analysis of partial resistance to Puccinia hordei in barley. [PDF]

PLoS ONE, 2010
BackgroundGenetic resistance to barley leaf rust caused by Puccinia hordei involves both R genes and quantitative trait loci. The R genes provide higher but less durable resistance than the quantitative trait loci. Consequently, exploring quantitative or
Xinwei Chen, Christine A Hackett, Rients E Niks, Peter E Hedley, Clare Booth, Arnis Druka, Thierry C Marcel, Anton Vels, Micha Bayer, Iain Milne, Iain Milne, Jenny Morris, Luke Ramsay, David Marshall, Linda Cardle, Robbie Waugh   +15 more
doaj   +3 more sources

Selenium in biology: Facts and medical perspectives [PDF]

, 2000
Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Flohé, Leopold, Gärtner, Roland, Köhrle, Josef, Brigelius-Flohé, Regina, Böck, August, Meyer, Ortwin   +5 more
core   +1 more source

Exogenous salicylic acid enhances wheat drought tolerance by influence on the expression of genes related to ascorbate-glutathione cycle

Biologia Plantarum, 2013
Treatment with 0.5 mM salicylic acid (SA) significantly alleviated growth inhibition induced by drought in wheat seedlings, manifested by less decreassed fresh mass, dry mass, plant height, root length, and less increased lipid peroxidation.
G. Z. Kang, G. Z. Li, G. Q. Liu, W. Xu, X. Q. Peng, C. Y. Wang, Y. J. Zhu, T. C. Guo   +7 more
doaj   +1 more source

Phospholipid Hydroperoxides Are Substrates for Non-selenium Glutathione Peroxidase [PDF]

Journal of Biological Chemistry, 1999
This study investigated phospholipid hydroperoxides as substrates for non-selenium GSH peroxidase (NSGPx), an enzyme also called 1-Cys peroxiredoxin. Recombinant human NSGPx expressed in Escherichia coli from a human cDNA clone (HA0683) showed GSH peroxidase activity with sn-2-linolenoyl- or sn-2-arachidonoyl-phosphatidylcholine hydroperoxides as ...
A B, Fisher, C, Dodia, Y, Manevich, J W, Chen, S I, Feinstein   +4 more
openaire   +2 more sources

Glutathione metabolism in Cryptocaryon irritans involved in defense against oxidative stress induced by zinc ions

Parasites & Vectors, 2022
Background Cryptocaryon irritans is a fatal parasite for marine teleosts and causes severe economic loss for aquaculture. Galvanized materials have shown efficacy in controlling this parasite infestation through the release of zinc ions to induce ...
Zhi-Hong Zhong, Zhi-Cheng Li, Han Li, Qing-Kai Guo, Chen-Xi Wang, Ji-Zhen Cao, An-Xing Li   +6 more
doaj   +1 more source

Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

Redox Biology, 2021
The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors.
Jeffrey M. Stolwijk, Jonathan A. Stefely, Mike T. Veling, Thomas J. van ‘t Erve, Brett A. Wagner, Thomas J. Raife, Garry R. Buettner   +6 more
doaj   +1 more source

Multigene families encode the major enzymes of antioxidant metabolism in Eucalyptus grandis L

Genetics and Molecular Biology, 2005
Antioxidant metabolism protects cells from oxidative damage caused by reactive oxygen species (ROS). In plants, several enzymes act jointly to maintain redox homeostasis.
Felipe Karam Teixeira, Larissa Menezes-Benavente, Vinícius Costa Galvão, Márcia Margis-Pinheiro   +3 more
doaj   +1 more source

Ganoderma lucidum aqueous extract inducing PHGPx to inhibite membrane lipid hydroperoxides and regulate oxidative stress based on single-cell animal transcriptome

Scientific Reports, 2022
In this study, the single-cell eukaryotic model organism Tetrahymena thermophila was used as an experimental material to reveal the anti-aging mechanism of Ganoderma lucidum aqueous extract. After treatment with the G.
Wenqiao Ding, Xueying Zhang, Xiaoyu Yin, Qing Zhang, Ying Wang, Changhong Guo, Ying Chen   +6 more
doaj   +1 more source