Results 21 to 30 of about 10,873 (239)

Human macrophages limit oxidation products in low density lipoprotein [PDF]

, 2005
This study tested the hypothesis that human macrophages have the ability to modify oxidation products in LDL and oxidized LDL (oxLDL) via a cellular antioxidant defence system.
Dahlgren, C, Hultén, LM, Krettek, A, Marklund, SL, Ullström, C, Van Reyk, D, Wiklund, O   +6 more
core   +4 more sources

Glutathione metabolism in Cryptocaryon irritans involved in defense against oxidative stress induced by zinc ions

Parasites & Vectors, 2022
Background Cryptocaryon irritans is a fatal parasite for marine teleosts and causes severe economic loss for aquaculture. Galvanized materials have shown efficacy in controlling this parasite infestation through the release of zinc ions to induce ...
Zhi-Hong Zhong, Zhi-Cheng Li, Han Li, Qing-Kai Guo, Chen-Xi Wang, Ji-Zhen Cao, An-Xing Li   +6 more
doaj   +1 more source

Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

Redox Biology, 2021
The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors.
Jeffrey M. Stolwijk, Jonathan A. Stefely, Mike T. Veling, Thomas J. van ‘t Erve, Brett A. Wagner, Thomas J. Raife, Garry R. Buettner   +6 more
doaj   +1 more source

Ganoderma lucidum aqueous extract inducing PHGPx to inhibite membrane lipid hydroperoxides and regulate oxidative stress based on single-cell animal transcriptome

Scientific Reports, 2022
In this study, the single-cell eukaryotic model organism Tetrahymena thermophila was used as an experimental material to reveal the anti-aging mechanism of Ganoderma lucidum aqueous extract. After treatment with the G.
Wenqiao Ding, Xueying Zhang, Xiaoyu Yin, Qing Zhang, Ying Wang, Changhong Guo, Ying Chen   +6 more
doaj   +1 more source

Selenium in biology: Facts and medical perspectives [PDF]

, 2000
Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Brigelius-Flohé, Regina, Böck, August, Flohé, Leopold, Gärtner, Roland, Köhrle, Josef, Meyer, Ortwin   +5 more
core   +1 more source

Multigene families encode the major enzymes of antioxidant metabolism in Eucalyptus grandis L

Genetics and Molecular Biology, 2005
Antioxidant metabolism protects cells from oxidative damage caused by reactive oxygen species (ROS). In plants, several enzymes act jointly to maintain redox homeostasis.
Felipe Karam Teixeira, Larissa Menezes-Benavente, Vinícius Costa Galvão, Márcia Margis-Pinheiro   +3 more
doaj   +1 more source

Concentration of glutathione and expression of glutathione peroxidases 1 and 4 in fresh sperm provide a forecast of the outcome of cryopreservation of human spermatozoa [PDF]

, 2004
Oxidative stress imbalance potentially leads to damage of the structure of the cell and macromolecules such as plasma membrane components, proteins, and DNA.
Garrido, N., Meseguer Anastasio, Manuel Francisco, Pellicer Martínez, Antonio, Remohí Giménez, José, Simón Vallés, Carlos   +4 more
core   +1 more source

Effects of trichotecene mycotoxins on gene expression and activity of glutathione redox system in common carp (Cyprinus carpio L.)

Frontiers in Marine Science, 2015
The purpose of present study was to evaluate the short- and long-term effects of T-2 toxin and deoxynivalenol (DON) in common carp. Short-term effect was evaluated using single oral doses of DON or T-2 toxin of 0.25, 0.50 or 3.00 mg/kg b.w ...
Csilla Pelyhe, Erika Zándoki, Balázs Kovács   +2 more
doaj   +1 more source

Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

Journal of Nanobiotechnology, 2023
Background Ferroptosis, a unique form of non-apoptotic cell death, is dependent on iron and lipoperoxidation, and has been shown to be associated with the pathogenesis of inflammatory bowel disease (IBD).
Zhiping Wei, Sanhua Hang, Dickson Kofi Wiredu Ocansey, Zhaoyang Zhang, Bo Wang, Xu Zhang, Fei Mao   +6 more
doaj   +1 more source

Kodierungsvielfalt der Phospholipid-Hydroperoxid Glutathion Peroxidase Untersuchungen zur Expressionsregulation des Enzyms in tierischen Geweben [PDF]

, 2003
Selenhaltige Glutathion-Peroxidasen bilden eine Familie antioxidativer Enzyme, die in der Lage sind organische und anorganische Hydroperoxide in die entsprechenden Hydroxide zu reduzieren.
Borchert, Astrid
core   +1 more source