Results 171 to 180 of about 37,055 (269)

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Dissecting the Radioresponse Heterogeneity of Lung Adenocarcinoma Cells From the Perspective of Transcriptional and Regulatory Landscape

MedComm, Volume 7, Issue 11, November 2026.
Radiation‐associated transcriptional and regulatory cell states drive heterogeneous radioresponses in isogenic lung adenocarcinoma cells. ABSTRACT Radioresistance severely compromises radiotherapy efficacy for lung adenocarcinoma (LUAD), yet the intrinsic heterogeneity of cellular radioresponses among isogenic tumor cells remains poorly characterized ...
Huan Tao, Yaru Li, Leixin Ge, Lu Chen, Yang Zheng, Feiyue Ma, Changhui Ge, Hanjiang Fu, Yu Sun, Longteng Wang, Junting Wang, Xuemei Bai, Hao Li, Xiaochen Bo, Hebing Chen, Xiaofei Zheng   +15 more
wiley   +1 more source

Phosphoproteomic profiling reveals reversal of dysregulated kinase signaling by nitric oxide inhibition in the Shank3 mouse model of autism. [PDF]

Sci Rep
Ginzburg S, Khaliulin I, Kartawy M, Hamoudi W, Amal H.   +4 more
europepmc   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, Volume 46, Issue 6, Page 1735-1752, November 2026.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Distinct molecular adaptations underlie convergent phenotypic responses to mannose in normal and metastatic melanocytes. [PDF]

Mol Cell Biochem
de Vasconcellos Racorti N, Lima LRF, Bustos SO, Salardani M, Barcick U, de Campos CBL, Pauletti BA, Leme AFP, Chammas R, Zelanis A.   +9 more
europepmc   +1 more source

Nucleolin Alterations and ROS Production Associate With Sensitivity of AML Cells to Venetoclax

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Venetoclax‐induced Bcl‐2 inhibition corresponds with Mcl‐1 attenuation and decrease of Nucleolin (NCL) level and activity in sensitive cells. Simultaneously, distinct cell subpopulations with opposite mitochondrial (CellROX label, magenta) and cellular (H2DCFDA stain, green) ROS occur, and the H2DCFDA‐positive population shows markers of early ...
Kateřina Wolfová, Petra Otevřelová, Barbora Brodská   +2 more
wiley   +1 more source

Characterization of Fiber-Type Composition and Phosphoproteins of Fast- and Slow-Growing Broilers. [PDF]

Animals (Basel)
Li Y, Huo W, Weng K, Liu J, Gu Y, Cai Y, Zhang Y, Zhang Y, Hu X, Chen G, Xu Q.   +10 more
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage-Specific Signalling and Metabolism in Equine Melanocytic Neoplasm. [PDF]

Vet Comp Oncol
Srimontri P, Kingkaw A, Prapaiwan N, Sujittosakul R, Iamkaewprasert N, Piputwat J, Isama-Al P, Munkongdee T, Chotikaprakal T, Yanyongsirikarn P, Phaonakrop N, Roytrakul S, Vongsangnak W, Tesena P.   +13 more
europepmc   +1 more source

Studies on the phosphoproteins of brain. 3. Phosphorylserine sequences in brain phosphoprotein [PDF]

Biochemical Journal, 1961
openaire   +2 more sources

Mycorrhiza-induced resistance against Botrytis cinerea in tomato operates through the systemin signalling cascade. [PDF]

New Phytol
Pastor-Fernandez J, Manresa-Grao M, Sánchez-Bel P, Andrés-Moreno S, Pozo MJ, Pastor V, Flors V.   +6 more
europepmc   +1 more source