Results 11 to 20 of about 18,478 (212)
Molecular Responses to Climate Change: How Warming and Acidification Reshape the Proteome and Phosphoproteome of the Endangered Mira Chub. [PDF]
Ecol EvolABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
Moreno JM +5 more
europepmc +2 more sources
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
Spatiotemporally resolved subcellular phosphoproteomics [PDF]
Proceedings of the National Academy of Sciences, 2021 Significance As one of the most important post-translational modifications, phosphorylation is both highly abundant and dynamically regulated in cells. Characterizing subcellular phosphoproteome with high temporal resolution should shed light on their contributions to diverse cellular processes.
Yanjun Liu +6 more
openaire +2 more sources
Quantitative plant phosphoproteomics [PDF]
Current Opinion in Plant Biology, 2011 Protein phosphorylation is a major post-translational modification in plants crucial for the regulation of diverse cellular functions. In the early stages of this field, efforts were focused on the qualitative detection, identification, and cataloging of in vivo protein phosphorylation sites.
Kelli G, Kline-Jonakin +2 more
openaire +2 more sources
Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit
Cell Reports, 2019 Summary: Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate chromosome segregation and for completion of the cell division cycle during exit from mitosis. In budding yeast, the Cdc14 phosphatase is thought to be a
Sandra A. Touati +5 more
doaj +1 more source
Plants, 2023 Brassinosteroids are a recently discovered group of substances that promote plant growth and productivity. Photosynthesis, which is vital for plant growth and high productivity, is strongly influenced by brassinosteroid signaling.
Hui Li +5 more
doaj +1 more source
Nigericin-Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis. [PDF]
ProteomicsABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Bhushan V +5 more
europepmc +2 more sources
Investigating the effect of target of rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets [PDF]
, 2019 Recuperado de: https://www.biorxiv.org/content/10.1101/310102v1Target of rapamycin (TOR) kinase is a conserved regulator of cell growth whose activity is modulated in response to nutrients, energy and stress.
Couso Liáñez, Inmaculada Concepción +6 more
core +1 more source
Frontiers in Veterinary Science, 2023 IntroductionCystic echinococcosis (CE) is a chronic zoonosis caused by infection with the metacestode of the Echinococcus granulosus. A unique characteristic of E.
Zhengrong Wang +14 more
doaj +1 more source
Molecules, 2023 Diabetic nephropathy (DN) contributes to increased morbidity and mortality among patients with diabetes and presents a considerable global health challenge. However, reliable biomarkers of DN have not yet been established.
Qing Li +8 more
doaj +1 more source