Results 51 to 60 of about 20,263 (273)

Induction of Macrophage Function in Human THP-1 Cells is Associated with MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase

Frontiers in Cell and Developmental Biology, 2016
Macrophages represent the primary human host response to pathogen infection and link the immediate defense to the adaptive immune system. Mature tissue macrophages convert from circulating monocyte precursor cells by terminal differentiation in a process
Erik eRichter, Katharina eVentz, Manuela eHarms, Joerg eMostertz, Falko eHochgräfe   +4 more
doaj   +1 more source

Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions [PDF]

, 2015
Little is known about the role of global phosphorylation events in the control of prokaryote metabolism. By performing a detailed analysis of all protein phosphorylation events previously reported in Escherichia coli, dynamic changes in protein ...
Jacob, Shana, Lim, SooA, Marcellin, Esteban, Nielsen, Lars K.   +3 more
core   +1 more source

Role of Protein Phosphorylation in the Regulation of Cell Cycle and DNA-Related Processes in Bacteria [PDF]

, 2016
In all living organisms, the phosphorylation of proteins modulates various aspects of their functionalities. In eukaryotes, protein phosphorylation plays a key role in cell signaling, gene expression, and differentiation.
Derouiche, Abderahmane, Garcia-Garcia, Transito, Mijakovic, Ivan, Noirot-Gros, Marie-Francoise, Poncet, Sandrine, Shi, Lei   +5 more
core   +4 more sources

Proteomics Analysis of Duck Lung Tissues in Response to Highly Pathogenic Avian Influenza Virus

Microorganisms
Domestic ducks (Anas platyrhynchos domesticus) are resistant to most of the highly pathogenic avian influenza virus (HPAIV) infections. In this study, we characterized the lung proteome and phosphoproteome of ducks infected with the HPAI H5N1 virus (A ...
Periyasamy Vijayakumar, Anamika Mishra, Ram Pratim Deka, Sneha M. Pinto, Yashwanth Subbannayya, Richa Sood, Thottethodi Subrahmanya Keshava Prasad, Ashwin Ashok Raut   +7 more
doaj   +1 more source

Peanut stunt virus and its satellite RNA trigger changes in phosphorylation in N-benthamiana infected plants at the early stage of the infection [PDF]

, 2018
Signaling in host plants is an integral part of a successful infection by pathogenic RNA viruses. Therefore, identifying early signaling events in host plants that play an important role in establishing the infection process will help our understanding ...
De Smet, Ive, Gevaert, Kris, Obrepalska-Steplowska, Aleksandra, Vu, Lam Dai, Wrzesinska, Barbara   +4 more
core   +2 more sources

Global Phosphoproteomics Analysis of IBRS-2 Cells Infected With Senecavirus A

Frontiers in Microbiology, 2022
Phosphorylation is a widespread posttranslational modification that regulates numerous biological processes. Viruses can alter the physiological activities of host cells to promote virus particle replication, and manipulating phosphorylation is one of ...
Jieyi Li, Zhongwang Zhang, Zhongwang Zhang, Jianliang Lv, Jianliang Lv, Zhongyuan Ma, Li Pan, Li Pan, Yongguang Zhang, Yongguang Zhang   +9 more
doaj   +1 more source

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source

Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated interconversion of phosphoforms [PDF]

, 2018
Wheat (Triticum ssp.) is one of the most important human food sources. However, this crop is very sensitive to temperature changes. Specifically, processes during wheat leaf, flower, and seed development and photosynthesis, which all contribute to the ...
Ahammed, Akter, Arnold, Asseng, Asthir, Barber, Beltrao, Bennett, Biasini, Boden, Bonhomme, Box, Brenchley, Brigitte van de Cotte, Chan, Chen, Cherkasov, Chou, Cox, Cox, de Leonardis, De Storme, de Zelicourt, Ding, Dory, Draeger, Dutta, Facette, Farooq, Fischer, Franklin, Galli, Gallie, Gan, Gray, Gupta, Guy, Hasanuzzaman, Hashiguchi, Hawkesford, Hayes, Hedhly, Hofmann, Huang, Ibañez, Inge Verstraeten, International Wheat Genome Sequencing Consortium (IWGSC), IPCC, Ive De Smet, Jagadish, Jia, Jung, Karijolich, Ki, Kilisch, Kim, Kline, Kosová, Kotak, Kris Gevaert, Kumar, Kumar, Kumar, Laino, Lam Dai Vu, Lamberti, Lawrence, Legris, Li, Ling, Liu, Lu, Luo, Majoul, Merret, Mochida, Nguyen, Nishi, Nussinov, Oikawa, O’Connor, Pflum, Porter, Pécrix, Qi, Quint, Rampitsch, Raschke, Rizhsky, Ruan, Rust, Saini, Saini, Salazar, Scalabrin, Schmitz, Schönichen, Shalgi, Steffens, Strittmatter, Sun, Sun, Suzuki, Tingting Zhu, van Wijk, Vignali, Vizcaíno, Vizcaíno, Vu, Vu, Wagner, Wang, Wang, Wang, Wardlaw, Weller, Wilkinson, Wu, Xu, Xu, Xue, Yang, Yang, Yu, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhen, Zhu, Zinn, Zourelidou   +133 more
core   +3 more sources

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

Open Biology, 2021
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the ...
Lenka Halova, David Cobley, Mirita Franz-Wachtel, Tingting Wang, Kaitlin R. Morrison, Karsten Krug, Nicolas Nalpas, Boris Maček, Iain M. Hagan, Sean J. Humphrey, Janni Petersen   +10 more
doaj   +1 more source

ANIA:ANnotation and Integrated Analysis of the 14-3-3 interactome [PDF]

, 2014
The dimeric 14-3-3 proteins dock onto pairs of phosphorylated Ser and Thr residues on hundreds of proteins, and thereby regulate many events in mammalian cells.
Baskaran, Bastea, Bier, Carol MacKintosh, Cock, Cohen, Dickerson, Dinkel, Dubois, Edgar, Forbes, Fábio Madeira, Gavuthami Murugesan, Gerta Hoxhaj, Graves, Green, Hornbeck, Hu, Huang da, Huminiecki, Ichimura, Johnson, Johnson, Kasahara, Katoh, Konig, Larance, Larkin, Linding, Makino, Manning, Michele Tinti, Molzan, Notredame, Obenauer, Ostlund, Panni, Pearce, Rachel Toth, Robens, Sievers, Silhan, Tinti, Uhart, UniProt Consortium, Waterhouse, Yaffe, Yaffe, Zanivan, Zanivan, Zhang, Zhao   +51 more
core   +3 more sources