Results 71 to 80 of about 20,263 (273)

Phosphoproteomics

, 2012
The book provides an overview of state-of-art techniques for the purification, analysis and quantification of proteins in complex samples using different enrichment strategies.
F. Lonardoni, BOSSI, Alessandra Maria
openaire   +3 more sources

FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism [PDF]

, 2019
A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which translocate from the nucleus to the cytoplasm following insulin-stimulated phosphorylation.
Albrechtsen, N., Araki, E., Batista, T., Cai, W., Cederquist, C., Damasio, M., Enerback, S., Gupta, M., Homan, E., Kahn, C., Mann, M., Ramirez, A., Sakaguchi, M., Singh, S., Steger, M., Wang, C.   +15 more
core   +2 more sources

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

LymPHOS 2.0: An update of a phosphosite database of primary human T cells [PDF]

, 2017
LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes.
Abián, Joaquín, Carrascal, Montserrat, Gallardo, Oscar, Nguyen, T. D., Vidal Cortes, Oriol   +4 more
core   +1 more source

Chilling stress response in tobacco seedlings: insights from transcriptome, proteome, and phosphoproteome analyses

Frontiers in Plant Science
Tobacco (Nicotiana tabacum L.) is an important industrial crop, which is sensitive to chilling stress. Tobacco seedlings that have been subjected to chilling stress readily flower early, which seriously affects the yield and quality of their leaves ...
Xiuhong Shao, Zhenchen Zhang, Faheng Yang, Yongchao Yu, Junjie Guo, Jiqin Li, Tingyu Xu, Xiaoying Pan   +7 more
doaj   +1 more source

Assessment of Protein Content and Phosphorylation Level in Synechocystis sp. PCC 6803 under Various Growth Conditions Using Quantitative Phosphoproteomic Analysis

Molecules, 2020
The photosynthetic apparatus and metabolic enzymes of cyanobacteria are subject to various controls, such as transcriptional regulation and post-translational modifications, to ensure that the entire cellular system functions optimally.
Masakazu Toyoshima, Yuma Tokumaru, Fumio Matsuda, Hiroshi Shimizu   +3 more
doaj   +1 more source

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

The FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast, Christian Werner, Karsten Niefind, Joachim Jose   +3 more
wiley   +1 more source

Elucidating Host-Pathogen Interactions Based on Post-Translational Modifications Using Proteomics Approaches [PDF]

, 2015
Microbes with the capability to survive in the host tissue and efficiently subvert its innate immune responses can cause various health hazards. There is an inherent need to understand microbial infection patterns and mechanisms in order to develop ...
Jers, Carsten, Mijakovic, Ivan, Ravikumar, Vaishnavi   +2 more
core   +1 more source

Comparative Proteome and Phosphoproteome Analyses Reveal Different Molecular Mechanism Between Stone Planting Under the Forest and Greenhouse Planting of Dendrobium huoshanense

Frontiers in Plant Science, 2022
The highly esteemed Chinese herb, Dendrobium huoshanense, whose major metabolites are polysaccharides and alkaloids, is on the verge of extinction. The stone planting under the forest (SPUF) and greenhouse planting (GP) of D.
Liping Wu, Xiaoxi Meng, Huizhen Huang, Yingying Liu, Weimin Jiang, Xinglong Su, Zhaojian Wang, Fei Meng, Longhai Wang, Daiyin Peng, Daiyin Peng, Daiyin Peng, Shihai Xing, Shihai Xing, Shihai Xing   +14 more
doaj   +1 more source

A Water‐Saving Drought Survival Phenotype in a Wheat TILLING Mutant Involves Survival‐Biased Metabolic and Phosphorylation Reprogramming

Plant, Cell &Environment, EarlyView.
ABSTRACT Drought tolerance in crops often involves trade‐offs between water conservation, growth and reproduction. Understanding how water‐saving strategies are implemented at physiological and metabolic levels remains critical for improving crop performance under water‐limited conditions.
Ryosuke Mega, Shun‐ichiro Hirata, Kota Yamashita, Hinano Takase, Taishi Umezawa, Yasuko Watanabe, June‐Sik Kim, Tomoyuki Kosaka, Akihiro Nieda, Hisashi Tsujimoto   +9 more
wiley   +1 more source