Results 71 to 80 of about 12,382 (182)
Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion
Advanced Science, Volume 13, Issue 56, 9 October 2026.This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong +17 morewiley +1 more sourceImprovement of the Quantification Accuracy and Throughput for Phosphoproteome Analysis by a Pseudo Triplex Stable Isotope Dimethyl Labeling Approach
, 2011 Improvement of the Quantification Accuracy and Throughput for Phosphoproteome Analysis by a Pseudo Triplex Stable Isotope Dimethyl Labeling ApproachAccurately quantifying the changes of phosphorylation level on specific sites is crucial to understand the Song, Chunxia, DanielFigeys, Wang, Fangjun, Wang, Hongyang, Figeys, Daniel, Zou, Hanfa, 邹汉法, Ye, Mingliang, Zhu, Jun, Chen, Rui, Cheng, Kai, Tan, Yexiong +11 morecore +1 more sourceList of TMT reagents and reporter ions used for each sample in two independent global phosphoproteome studies.
, 2021 List of TMT reagents and reporter ions used for each sample in two independent global phosphoproteome studies.Victoria C. Pham (7388111), Lino C. Gonzalez (11812916), Jillian L. Astarita (11812907), Shilpa Keerthivasan (11812910), Erik Verschueren (753511), Jennie R. Lill (212568), Andrew A. Pierce (4413523), Shannon J. Turley (11812922), Sean M. Peterson (11812913), Nadia Martinez-Martin (11812919), Yasin Şenbabaoğlu (2543956), Bushra Husain (1430635), Sarah Gierke (6560351), Cecile Chalouni (1593517) +13 morecore +1 more sourceGenetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models
Advanced Science, Volume 13, Issue 58, 19 October 2026.Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna +22 morewiley +1 more sourceSupplementary Table 7 from Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts
Supplementary Table 7.Zoi E. Sychev (18492172), Ella Boytim (18492181), Peter S. Nelson (15044327), Justin H. Hwang (18492187), Atef Ali (15925702), Hannah E. Bergom (15925687), Megan Ludwig (18492178), Stephen R. Plymate (16918277), Abderrahman Day (15925690), Justin M. Drake (15082222), Ilsa Coleman (18492184), Eva Corey (14845888), Gabrianne Larson (18492175) +12 morecore +1 more sourceSupplementary Table 14 from Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts
Supplementary Table 14.Zoi E. Sychev (18492172), Ella Boytim (18492181), Peter S. Nelson (15044327), Justin H. Hwang (18492187), Atef Ali (15925702), Hannah E. Bergom (15925687), Megan Ludwig (18492178), Stephen R. Plymate (16918277), Abderrahman Day (15925690), Justin M. Drake (15082222), Ilsa Coleman (18492184), Eva Corey (14845888), Gabrianne Larson (18492175) +12 morecore +1 more sourceSupplementary Table 8 from Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts
Supplementary Table 8.Zoi E. Sychev (18492172), Ella Boytim (18492181), Peter S. Nelson (15044327), Justin H. Hwang (18492187), Atef Ali (15925702), Hannah E. Bergom (15925687), Megan Ludwig (18492178), Stephen R. Plymate (16918277), Abderrahman Day (15925690), Justin M. Drake (15082222), Ilsa Coleman (18492184), Eva Corey (14845888), Gabrianne Larson (18492175) +12 morecore +1 more source