Results 91 to 100 of about 20,263 (273)

Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks [PDF]

, 2009
The mammalian postsynaptic density (PSD) comprises a complex collection of ~1100 proteins. Despite extensive knowledge of individual proteins, the overall organization of the PSD is poorly understood.
Choudhary, Jyoti S, Coba, Marcelo P, Collins, Mark O, Croning, Mike D R, Grant, Seth G N, Kopanitsa, Maksym V, Pocklington, Andrew J, Swamy, Sajani, Uren, Rachel T   +8 more
core   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

Proteome Profiling of Wheat Shoots from Different Cultivars [PDF]

, 2017
Wheat is a cereal grain and one of the world's major food crops. Recent advances in wheat genome sequencing are by now facilitating its genomic and proteomic analyses.
Elisabeth Stes, Frederik Coppens, Inge Verstraeten, Ive De Smet, Kris Gevaert, Lam Dai Vu, Michiel Van Bel   +6 more
core   +1 more source

Post‐translational Modifications in Proteins: Prediction Methods, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Posttranslational modifications (PTMs) serve as rapid and reversible molecular switches that reshape protein activity, stability, and interactomes, thereby governing virtually all physiological cues ranging from signal transduction to epigenetic memory. Mass spectrometry‐based proteomics has substantially expanded our understanding of PTM emergence and
Shuning Zhang, Jingmin Li, Meihuan Chen, Hailong Huang   +3 more
wiley   +1 more source

Heat Shock Protein 20 (HSP20) is a novel substrate for Protein Kinase D1 (PKD1) [PDF]

, 2015
Heat shock protein 20 (HSP20) has cardioprotective qualities, which are triggered by PKA phosphorylation. PKD1 is also a binding partner for HSP20, and this prompted us to investigate whether the chaperone was a substrate for PKD1.
Baillie, George, Sin, Yuan Yan
core   +1 more source

Stable isotopic labeling in proteomics [PDF]

, 2008
Labeling of proteins and peptides with stable heavy isotopes (deuterium, carbon-13, nitrogen-15, and oxygen-18) is widely used in quantitative proteomics.
Beynon, Blagoev, Borisov, Browder, Choe, Conrads, Craig, de Godoy, De Leenheer, Dean, Desiderio, Enoksson, Gerber, Gevaert, Gevaert, Gevaert, Gevaert, Gevaert, Gonzalez, Gronborg, Gruhler, Gygi, Hansen, Harsha, Hsu, Hsu, Hsu, Impens, Ji, Krijgsveld, Kuster, Kuster, Lange, Lanquar, Lopez-Otin, MacCoss, Mann, Mason, Mirzaei, Munchbach, Oda, Ong, Ong, Overall, Pan, Perkins, Pratt, Rivers, Ross, Schmidt, Schnolzer, Schulze, Scott, Selbach, Sethuraman, Staes, Staes, Tam, Van Damme, Van Hoof, Vande Walle, Wahlander, Wang, Washburn, Wiese, Wu, Zhang, Zhang, Zhang, Zhou   +69 more
core   +2 more sources

Systems Biology of Recombinant 2G12 and 353/11 mAb Production in CHO-K1 Cell Lines at Phosphoproteome Level

Proteomes
Background: Chinese hamster ovary (CHO) cells are extensively used in the pharmaceutical industry for producing complex proteins, primarily because of their ability to perform human-like post-translational modifications.
Eldi Sulaj, Felix L. Sandell, Linda Schwaigerlehner, Gorji Marzban, Juliane C. Dohm, Renate Kunert   +5 more
doaj   +1 more source

Data-Independent Acquisition-Based Proteome and Phosphoproteome Profiling Reveals Early Protein Phosphorylation and Dephosphorylation Events in Arabidopsis Seedlings upon Cold Exposure [PDF]

, 2021
Jinjuan Tan, Zhongjing Zhou, Hanqian Feng, Jiayun Xing, Yujie Niu, Zhiping Deng   +5 more
openalex   +1 more source

Masters of perception: phosphorylation‐dependent signaling in plants

New Phytologist, Volume 250, Issue 1, Page 89-94, April 2026.
Summary Plants are masters of perception, reacting to a myriad of biochemical and physical cues in a constantly changing environment. Plants rely on local cell‐based signal processing to perceive and react sufficiently fast to a multitude of stimuli. The ability to respond quickly is crucial for sustaining growth, defense, and metabolism and thereby ...
Mark Roosjen, Justin W. Walley, Dolf Weijers   +2 more
wiley   +1 more source

Phosphoproteomics v1 [PDF]

, 2017
Proteins from the spinal ligament cells of wild-type and null mice were separated using two-dimensional gel electrophoresis and stained with Pro-Q Diamond phosphoprotein gel stain (Thermo Fisher Scientific, Waltham, MA, USA) followed by SYPRO Ruby protein gel stain (Thermo Fisher Scientific).
openaire   +1 more source