Results 101 to 110 of about 465,841 (199)

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 47, 24 August 2026.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

Cell-bound phosphatase activity in cotton (gossypium hirsutum L.) roots [PDF]

open access: yes, 1995
A study was made of phosphorus nutrition in cotton cultivars derived from Pakistan with particular reference to phosphatase activity. Cultivars used were Qalandri, Rehmani, Reshami and TH-3/83; Qalandri was used for most of the phosphatase ...
Baloch, Gul Muhammad M.
core  

Enhanced phosphoserine insertion during Escherichia coli protein synthesis via partial UAG codon reassignment and release factor 1 deletion [PDF]

open access: yes, 2012
Genetically encoded phosphoserine incorporation programmed by the UAG codon was achieved by addition of engineered elongation factor and an archaeal aminoacyl-tRNA synthetase to the normal Escherichia coli translation machinery (Park et al., 2011 ...
Isaacs, Farren J.   +9 more
core   +1 more source

Synthesis and characterization of l-3-(pentafluorophosphato-difluoromethyl)-alanine, a structural and functional mimetic of phosphoserine [PDF]

open access: yes
Serine phosphorylation is an essential switch for regulating the interactions and functions of many disease-related proteins. Accordingly, stable phosphoserine mimetics constitute chemical tools to study the effects of these post-translational ...
Tiemann, Markus   +6 more
core   +1 more source

Modulating the serine metabolism in human differentiated astrocytes: an integrated multi omics approach

open access: yesFrontiers in Cellular Neuroscience
IntroductionAstrocytes are the major source of L-serine (L-Ser) in the brain: the glycolytic intermediate D-3-phosphoglycerate is converted into L-Ser through the phosphorylated pathway (PP) made up of three enzymes, phosphoglycerate dehydrogenase (PHGDH)
Farida Tripodi   +9 more
doaj   +1 more source

Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model

open access: yesAsian Journal of Andrology, 2019
Epididymitis is a commonly diagnosed disease associated with male infertility. However, little is known about the molecules that are involved in its development.
Xin Song   +5 more
doaj   +1 more source

Functional characterisation of a predicted chloroplastic plant protein phosphatase [PDF]

open access: yes, 2009
The phosphatase AtPTPKISI is involved in the control of starch metabolism in Arabidopsis thaliana leaves at night. The SEX4 (Starch Excess 4) mutants, lacking this predicted phosphatase, have strongly reduced rates of starch metabolism.
Seymour, Michael David John
core  

A comparison of phosphoserine phosphatase in two allelic serine requiring mutants of Neurospora crassa

open access: yes, 1980
Includes bibliographical references (pages 43-45)The phosphorylated pathway has been proposed as the major source of serine in Neurospora Crassa (Sojka & Garner, 1967).
Dodson, Snowdy Denise
core  

A study of the root surface phosphatase activities of three species of higher plants: Juncus effusus, Phragnutes australis, and Typha latifolia [PDF]

open access: yes, 1993
The aim of this project was to investigate a possible link between environmental phosphorus status and the root surface phosphatase activities of three species of emergent macrophytes, with a view to assessing their potential for use as "biondicators ...
Luff, Heather
core  

A new histochemical method using human placenta alkaline phosphatase for demonstrating concanavalin A binding sites on cell surfaces [PDF]

open access: yes, 1975
Human placenta alkaline phosphatase (HP-ALP), a glycoprotein, was stained histochemically for the purpose of examining the concanavalin A (Con A) binding sites on the cell surface. HP-ALP was bound to the cell surface by Con A.
Oda, Takuzo   +2 more
core   +1 more source

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