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Expression of -3-Phosphoserine Phosphatase Is Regulated by Reconstituted Basement Membrane

Biochemical and Biophysical Research Communications, 2001
Reconstituted basement membrane (Matrigel) promotes differentiation of endometrial adenocarcinoma cells in vitro. However, little is known about the molecular basis of these in vitro differentiation processes. Using differential display RT-PCR to search for potential molecular markers we screened for genes which respond to contact to basement membrane ...
E, Strunck   +3 more
openaire   +2 more sources

Inhibition of phosphoserine phosphatase enhances the anticancer efficacy of 5-fluorouracil in colorectal cancer.

Biochemical and Biophysical Research Communications, 2016
Most colorectal cancer (CRC) cell lines are identified to overexpress phosphoserine phosphatase (PSPH), which regulates the intracellular synthesis of serine and glycine, and supports tumor growth. In this study, the effect of PSPH on 5-fluorouracil (5-FU) efficacy was evaluated.
Xin Li, Zhe Xun, Yong Yang
semanticscholar   +3 more sources

Why calcium inhibits magnesium-dependent enzyme phosphoserine phosphatase? A theoretical study

Theoretical Chemistry Accounts, 2012
Phosphoserine phosphatase (PSP) utilizes one Mg2+ ion to catalyze the hydrolysis of phospho-l-serine. The displacement of Mg2+ by Ca2+ results in the loss of activity. The reaction mechanisms for the enzyme with both Mg2+ and Ca2+ bound were investigated using hybrid density functional theory.
Yang, L.   +5 more
openaire   +2 more sources

o-Phosphoserine phosphatase

Biochimica et Biophysica Acta, 1958
F C, NEUHAUS, W L, BYRNE
openaire   +2 more sources

Phosphoserine phosphatase

1991
Dietmar Schomburg, Margit Salzmann
openaire   +1 more source

Investigation of bound and unbound phosphoserine phosphatase conformations through elastic network models and molecular dynamics simulations

Journal of Biomolecular Structure and Dynamics, 2021
Laurence Leherte   +2 more
exaly  

Biochemical characterization of phosphoserine phosphatase SerB2 from

Biochemical and Biophysical Research Communications, 2020
Johan Wouters, Elise Pierson
exaly  

Interactions of aminophosphonates with rat liver phosphoserine phosphatase

Biochemical Society Transactions, 1985
YOLANDE VIDAL   +2 more
openaire   +1 more source

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