Results 91 to 100 of about 40,216 (223)
The effect of phospho-peptide on the stability of gold nanoparticles and drug delivery
Journal of Nanobiotechnology, 2019 Background Gold nanoparticles (AuNPs) have been proposed for many applications in medicine and bioanalysis. For use in all these applications, maintaining the stability of AuNPs in solution by suppressing aggregation is paramount.
Zhanwu Hou +7 more
doaj +1 more source
Cell Biology International, Volume 50, Issue 7, July 2026.ABSTRACT The Epidermal Growth Factor Receptor (EGFR) is a key regulator of neurodevelopment, controlling the proliferation, differentiation, and self‐renewal of neural stem and progenitor cells. Dysregulated EGFR signaling has been implicated in schizophrenia, a neurodevelopmental disorder associated with abnormal cortical maturation.
Tommaso Toffanin +17 more
wiley +1 more source
The Phosphotyrosine Binding-like Domain of Talin Activates Integrins*
Journal of Biological Chemistry, 2002 Cellular regulation of the ligand binding affinity of integrin adhesion receptors (integrin activation) depends on the integrin β cytoplasmic domains (tails). The head domain of talin binds to several integrin β tails and activates integrins.
D. Calderwood +6 more
semanticscholar +1 more source
Phosphotyrosine signaling and the single cell:metazoan boundary [PDF]
Proceedings of the National Academy of Sciences, 1997 Systematists classify together three groups of organisms that are referred to as “slime molds,” the Myxogastria, Dictyostelia, and Protostelia (3). The Protostelids are the least studied. The Myxogastria include the well studied Physarum polycephalum, a prototypical single-celled ameba that can also form a large multinucleate plasmodium (4 ...
openaire +2 more sources
The language of SH2 domain interactions defines phosphotyrosine‐mediated signal transduction
FEBS Letters, 2012 Natural languages arise in an unpremeditated fashion resulting in words and syntax as individual units of information content that combine in a manner that is both complex and contextual, yet intuitive to a native reader.
Bernard A. Liu, B. Engelmann, Piers Nash
semanticscholar +1 more source
Phosphotyrosine profiling of curcumin-induced signaling
Clinical Proteomics, 2016 Curcumin, derived from the rhizome Curcuma longa, is a natural anti-cancer agent and has been shown to inhibit proliferation and survival of tumor cells. Although the anti-cancer effects of curcumin are well established, detailed understanding of the signaling pathways altered by curcumin is still lacking.
Gajanan Sathe +14 more
openaire +4 more sources
Parallel Assessment of Tyrosine Phosphorylation and Nuclear Targeting of Proteins
BioTechniques, 2001 Phosphotyrosine signaling plays a vital role in cell regulation—from receptor activation, through stimulation of signal networks and nuclear targeting, to final cellular responses.
A. Kulyte +4 more
doaj +1 more source
An enriching phosphotyrosine experience for Src substrates [PDF]
Journal of Proteome Research, 2008 To find more substrates of Src, a protein implicated in some cancers, researchers focused on phosphotyrosine-modified proteins.
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Phosphotyrosine recognition domains: the typical, the atypical and the versatile
Cell Communication and Signaling, 2012 SH2 domains are long known prominent players in the field of phosphotyrosine recognition within signaling protein networks. However, over the years they have been joined by an increasing number of other protein domain families that can, at least with ...
T. Kaneko +3 more
semanticscholar +1 more source
Neuroligin-1 dependent phosphotyrosine signaling in excitatory synapse differentiation
Frontiers in Molecular NeuroscienceIntroductionThe synaptic adhesion molecule neuroligin-1 (NLGN1) is involved in the differentiation of excitatory synapses, but the precise underlying molecular mechanisms are still debated.
Zsófia Szíber +5 more
doaj +1 more source