Results 81 to 90 of about 1,927 (190)
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg +3 more
wiley +1 more source
Continuous flow synthesis of azobenzenes via Baeyer–Mills reaction
Azobenzene, as one of the most prominent molecular switches, is featured in many applications ranging from photopharmacology to information or energy storage.
Jan H. Griwatz +2 more
doaj +1 more source
Smart photopharmacological agents: LaVO4:Eu3+@vinyl phosphonate combining luminescence imaging and photoswitchable butyrylcholinesterase inhibition. [PDF]
The combination of photoswitchability and bioactivity in one compound provides interesting opportunities for photopharmacology. Here, we report a hybrid compound that in addition allows for its visual localization.
Bikbaeva G +11 more
europepmc +3 more sources
Design of antibacterial molecules by photopharmacology (ECOPHOTOSKIN)
Antibiotics are rejected in the environment after their use for treating human and animal bacterial infections. These residues are poorly eliminated by the actual wastewater treatment processes, impacting both animal, human and environmental health. This led to the emergence of antibiotic resistance in bacterial pathogens. To fight this issue, the last
Aubert, Amélie +4 more
openaire +2 more sources
Optogenética y posibles terapias para la retinosis pigmentaria [PDF]
La retinosis pigmentaria (RP) es un grupo clínico y genéticamente heterogéneo de trastornos de la retina hereditarios caracterizados por una disfunción progresiva difusa de fotorreceptores predominantemente bastón, con la posterior degeneración de ...
Sansa Fayos, Marc
core
X‐ray controlled release strategy in cancer therapy
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan +5 more
wiley +1 more source
While photopharmacology enables precise spatiotemporal control over drug activity, its widespread reliance on UV‐responsive molecules often hinders preclinical and clinical advancements. Thus, alternative scaffolds can offer promising advantages over the
Leticia M. Lazinski +6 more
doaj +1 more source
Photopharmacology and photoresponsive drug delivery
This review outlines the applications of photopharmacology and photoresponsive drug delivery in controlling biological activities using light for diverse biomedical applications.
Yuwei Liu, Tianyi Wang, Weiping Wang
openaire +2 more sources
The key parameter for characterization of novel photoswitches is a half‐life of the metastable form. However, processing one kinetic data set by different approaches used in literature leads to a wide range of the half‐lives with up to 25% deviation, which may cause significant inconsistencies when comparing the photoswitchable systems.
Anna Hruzíková +2 more
wiley +1 more source
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological
Damien Lemoine +7 more
doaj +1 more source

