Results 81 to 90 of about 1,927 (190)

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

Continuous flow synthesis of azobenzenes via Baeyer–Mills reaction

open access: yesBeilstein Journal of Organic Chemistry, 2022
Azobenzene, as one of the most prominent molecular switches, is featured in many applications ranging from photopharmacology to information or energy storage.
Jan H. Griwatz   +2 more
doaj   +1 more source

Smart photopharmacological agents: LaVO4:Eu3+@vinyl phosphonate combining luminescence imaging and photoswitchable butyrylcholinesterase inhibition. [PDF]

open access: yesNanoscale Adv
The combination of photoswitchability and bioactivity in one compound provides interesting opportunities for photopharmacology. Here, we report a hybrid compound that in addition allows for its visual localization.
Bikbaeva G   +11 more
europepmc   +3 more sources

Design of antibacterial molecules by photopharmacology (ECOPHOTOSKIN)

open access: yes, 2023
Antibiotics are rejected in the environment after their use for treating human and animal bacterial infections. These residues are poorly eliminated by the actual wastewater treatment processes, impacting both animal, human and environmental health. This led to the emergence of antibiotic resistance in bacterial pathogens. To fight this issue, the last
Aubert, Amélie   +4 more
openaire   +2 more sources

Optogenética y posibles terapias para la retinosis pigmentaria [PDF]

open access: yes, 2019
La retinosis pigmentaria (RP) es un grupo clínico y genéticamente heterogéneo de trastornos de la retina hereditarios caracterizados por una disfunción progresiva difusa de fotorreceptores predominantemente bastón, con la posterior degeneración de ...
Sansa Fayos, Marc
core  

X‐ray controlled release strategy in cancer therapy

open access: yesBMEMat, Volume 3, Issue 4, December 2025.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan   +5 more
wiley   +1 more source

Bistable and Water‐Operable Hemiindigo Photoswitches Allow Optical Control of Acetylcholinesterase Activity with Visible Light

open access: yesChemistryEurope
While photopharmacology enables precise spatiotemporal control over drug activity, its widespread reliance on UV‐responsive molecules often hinders preclinical and clinical advancements. Thus, alternative scaffolds can offer promising advantages over the
Leticia M. Lazinski   +6 more
doaj   +1 more source

Photopharmacology and photoresponsive drug delivery

open access: yesChemical Society Reviews
This review outlines the applications of photopharmacology and photoresponsive drug delivery in controlling biological activities using light for diverse biomedical applications.
Yuwei Liu, Tianyi Wang, Weiping Wang
openaire   +2 more sources

How to (not) Evaluate a Photoswitch Performance; Benchmarking of Methods Used for Processing Kinetic Data on an Example of Arylazopyrazole Z‐Isomer Half‐Life

open access: yesChemistry–Methods, Volume 5, Issue 12, November 2025.
The key parameter for characterization of novel photoswitches is a half‐life of the metastable form. However, processing one kinetic data set by different approaches used in literature leads to a wide range of the half‐lives with up to 25% deviation, which may cause significant inconsistencies when comparing the photoswitchable systems.
Anna Hruzíková   +2 more
wiley   +1 more source

Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

open access: yeseLife, 2020
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological
Damien Lemoine   +7 more
doaj   +1 more source

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