TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment [PDF]
Cell Death and Disease, 2023 Retinal detachment (RD) occurs in several major retinal conditions and often causes irreversible vision loss due to photoreceptor cell death. Retinal residential microglial cells are activated following RD and participate in photoreceptor cell death via ...
Wenchuan Zhou +5 more
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Role of glycolysis in retinal vascular endothelium, glia, pigment epithelium, and photoreceptor cells and as therapeutic targets for related retinal diseases [PDF]
International Journal of Ophthalmology, 2021 Glycolysis produces large amounts of adenosine triphosphate (ATP) in a short time. The retinal vascular endothelium feeds itself primarily through aerobic glycolysis with less ATP.
Ting-Ting Yang, Hui Li, Li-Jie Dong
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Protocol for electron microscopy of Drosophila photoreceptor cells. [PDF]
STAR Protoc, 2022 Gu Q, Tian Y, Han J.
europepmc +2 more sources
Device-free isolation of photoreceptor cells from patient iPSC-derived retinal organoids [PDF]
JCI InsightAutologous photoreceptor cell replacement is one of the most promising strategies currently being developed for the treatment of patients with inherited retinal degenerative blindness.
Nicholas E. Stone +8 more
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Vitamin A aldehyde-taurine adducts function in photoreceptor cells. [PDF]
Redox Biol, 2022 Kim HJ, Zhao J, Sparrow JR.
europepmc +2 more sources
Human photoreceptor cells from different macular subregions have distinct transcriptional profiles. [PDF]
Hum Mol Genet, 2021 Voigt AP +9 more
europepmc +3 more sources
A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells. [PDF]
J Biol Chem, 2022 Cleghorn WM +8 more
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Bone marrow-derived mononuclear stem cells in the treatment of retinal degenerations
Neural Regeneration Research, 2022 Retinal degenerative diseases affecting the outer retina in its many forms (inherited, acquired or induced) are characterized by photoreceptor loss, and represent currently a leading cause of irreversible vision loss in the world.
Diego Garcia-Ayuso +4 more
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Tzu Chi Medical Journal, 2020 The visual impairment associated with inherited retinal degeneration and age-related degeneration of photoreceptors is causing substantial challenges in finding effective therapies.
Rupendra Shrestha +2 more
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Microfluidic processing of stem cells for autologous cell replacement
Stem Cells Translational Medicine, 2021 Autologous photoreceptor cell replacement is one of the most promising approaches currently under development for the treatment of inherited retinal degenerative blindness.
Nicholas E. Stone +4 more
doaj +1 more source