Results 71 to 80 of about 12,437 (221)

Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network

open access: yeseLife, 2023
Genetic studies in human and mice have established a dual role for Vsx genes in retina development: an early function in progenitors’ specification, and a later requirement for bipolar-cells fate determination. Despite their conserved expression patterns,
Joaquín Letelier   +12 more
doaj   +1 more source

Wave Mechanics of Ciliary Proteins: Quantum‐Enabled Sensing and Energy Transfer in the “Cellular Antenna”

open access: yesAggregate, Volume 7, Issue 6, June 2026.
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian   +5 more
wiley   +1 more source

Cephalochordate Melanopsin: Evolutionary Linkage between Invertebrate Visual Cells and Vertebrate Photosensitive Retinal Ganglion Cells

open access: yes, 2005
SummaryAnimal photoreceptor cells can be classified into two distinct types, depending on whether the photopigment is borne on the membrane of a modified cilium (ciliary type) or apical microvilli (rhabdomeric type) [1].
Tsukamoto, Hisao   +9 more
core   +1 more source

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

open access: yes, 2014
Peer ...
Findlay, Amy S.   +10 more
core   +1 more source

Gogo receptor contributes to retinotopic map formation and prevents R1-6 photoreceptor axon bundling. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:Topographic maps form the basis of neural processing in sensory systems of both vertebrate and invertebrate species. In the Drosophila visual system, neighboring R1-R6 photoreceptor axons innervate adjacent positions in the first optic ...
Irina Hein   +2 more
doaj   +1 more source

Cilia in Nervous System Development, Function, and Disease

open access: yesMedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Neural superposition and oscillations in the eye of the blowfly [PDF]

open access: yes, 1987
Neural superposition in the eye of the blowfly Calliphora erythrocephala was investigated by stimulating single photoreceptors using corneal neutralization through water immersion.
J. H. van Hateren   +2 more
core   +1 more source

Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina. [PDF]

open access: yesPLoS ONE, 2011
In the vertebrate retina, the Otx2 transcription factor plays a crucial role in the cell fate determination of both rod and cone photoreceptors. We previously reported that Otx2 conditional knockout (CKO) mice exhibited a total absence of rods and cones ...
Yoshihiro Omori   +8 more
doaj   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou   +11 more
wiley   +1 more source

Photoreceptor specific guanylate cyclases in vertebrate phototransduction

open access: yes, 2002
Two membrane bound guanylate cyclases are expressed in vertebrate photoreceptor cells. They serve a key function in photoreceptor physiology as they synthesize the intracellular transmitter of photoexcitation guanosine 3',5'-cyclic monophosphate (cGMP ...
Sharma, R. K., Duda, T., Koch, K.-W.
core   +1 more source

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