Results 71 to 80 of about 12,437 (221)
Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network
Genetic studies in human and mice have established a dual role for Vsx genes in retina development: an early function in progenitors’ specification, and a later requirement for bipolar-cells fate determination. Despite their conserved expression patterns,
Joaquín Letelier +12 more
doaj +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
SummaryAnimal photoreceptor cells can be classified into two distinct types, depending on whether the photopigment is borne on the membrane of a modified cilium (ciliary type) or apical microvilli (rhabdomeric type) [1].
Tsukamoto, Hisao +9 more
core +1 more source
Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]
Peer ...
Findlay, Amy S. +10 more
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Gogo receptor contributes to retinotopic map formation and prevents R1-6 photoreceptor axon bundling. [PDF]
BACKGROUND:Topographic maps form the basis of neural processing in sensory systems of both vertebrate and invertebrate species. In the Drosophila visual system, neighboring R1-R6 photoreceptor axons innervate adjacent positions in the first optic ...
Irina Hein +2 more
doaj +1 more source
Cilia in Nervous System Development, Function, and Disease
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
Neural superposition and oscillations in the eye of the blowfly [PDF]
Neural superposition in the eye of the blowfly Calliphora erythrocephala was investigated by stimulating single photoreceptors using corneal neutralization through water immersion.
J. H. van Hateren +2 more
core +1 more source
Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina. [PDF]
In the vertebrate retina, the Otx2 transcription factor plays a crucial role in the cell fate determination of both rod and cone photoreceptors. We previously reported that Otx2 conditional knockout (CKO) mice exhibited a total absence of rods and cones ...
Yoshihiro Omori +8 more
doaj +1 more source
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou +11 more
wiley +1 more source
Photoreceptor specific guanylate cyclases in vertebrate phototransduction
Two membrane bound guanylate cyclases are expressed in vertebrate photoreceptor cells. They serve a key function in photoreceptor physiology as they synthesize the intracellular transmitter of photoexcitation guanosine 3',5'-cyclic monophosphate (cGMP ...
Sharma, R. K., Duda, T., Koch, K.-W.
core +1 more source

