Results 91 to 100 of about 12,437 (221)

Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina

open access: yesScientific Reports, 2017
In the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods, cones, and melanopsin-expressing intrinsically photosensitive retinal ...
Xiwu Zhao, Kwoon Y. Wong, Dao-Qi Zhang
doaj   +1 more source

Widespread Variation in Retinochrome Spectral Absorbance Across Scallop Phylogeny

open access: yesMolecular Ecology, Volume 35, Issue 11, June 2026.
ABSTRACT Vision is a two‐step process, including phototransduction initiated by a retinal‐bound opsin photopigment, and subsequent photopigment regeneration wherein the inactive state is restored. Because retinal isomerization, or changing of the molecular structural conformation, drives the activation of opsin photopigments, the reverse process is a ...
Kyle E. McElroy   +3 more
wiley   +1 more source

Developmental dynamics of cone photoreceptors in the eel [PDF]

open access: yes, 2009
Background: Many fish alter their expressed visual pigments during development. The number of retinal opsins expressed and their type is normally related to the environment in which they live.
Bowmaker, JK   +11 more
core   +1 more source

Dual Knockout Models of the Spatially and Functionally Conserved rgra and rgrb Zebrafish Genes Reveal the Requirement of RGR for the Integrity of Cone‐Mediated Photopic Vision, the Photopic Visual Cycle and Bruch's Membrane Morphology

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin   +13 more
wiley   +1 more source

Photoreceptor Fate Determination in the Vertebrate Retina

open access: yes, 2018
Photoreceptors are highly specialized primary sensory neurons that sense light and initiate vision. This critical role is well demonstrated by the fact that visual impairment accompanies photoreceptor loss or dysfunction in many human diseases.
Wang, Sui, Cepko, Constance
core   +1 more source

Horizontal-cell like Dm9 neurons in Drosophila modulate photoreceptor output to supply multiple functions in early visual processing

open access: yesFrontiers in Molecular Neuroscience
Dm9 neurons in Drosophila have been proposed as functional homologs of horizontal cells in the outer retina of vertebrates. Here we combine genetic dissection of neuronal circuit function, two-photon calcium imaging in Dm9 and inner photoreceptors, and ...
Christopher Schnaitmann   +6 more
doaj   +1 more source

Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro. [PDF]

open access: yes, 1997
journal articleThe hedgehog gene family encodes secreted proteins important in many developmental patterning events in both vertebrates and invertebrates.
Levine, Edward M.   +1 more
core  

A comparative study of the potential for human retinal pigment epithelium utilising an embryonic chick model of the phenomenon

open access: yes, 2014
The retinal pigment epithelial (RPE) cells of several species, including: chicken, rat, mouse and newt, have been observed to undergo a phenomenon known as transdifferentiation.
Smart, MJK
core  

Directional Tuning Curves, Elementary Movement Detectors, and the Estimation of the Direction of Visual Movement [PDF]

open access: yes, 1990
Both the insect brain and the vertebrate retina detect visual movement with neurons having broad, cosine-shaped directional tuning curves oriented in either of two perpendicular directions.
Hateren, J.H. van, Hateren, J.H. van,
core   +1 more source

Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency

open access: yesFrontiers in Behavioral Neuroscience, 2018
The retina has an intrinsic circadian clock, but the importance of this clock for vision is unknown. Zebrafish offer many advantages for studying vertebrate vision and circadian rhythm. Here, we explored the role of zebrafish per2, a light-regulated gene,
Deng-feng Huang   +7 more
doaj   +1 more source

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