Results 91 to 100 of about 4,900,943 (176)
Encoding of light by the cone photoreceptor synapse [PDF]
, 2009 Retinal photoreceptors are the primary sensory neurons responsible for vertebrate vision. The photoreceptor converts light into a voltage signal that modulates neurotransmitter release at the photoreceptor synapse.
Jackman, Skyler Lofstrand
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Frontiers in Molecular NeuroscienceDm9 neurons in Drosophila have been proposed as functional homologs of horizontal cells in the outer retina of vertebrates. Here we combine genetic dissection of neuronal circuit function, two-photon calcium imaging in Dm9 and inner photoreceptors, and ...
Christopher Schnaitmann +6 more
doaj +1 more source
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? [PDF]
, 2005 PURPOSE: We previously demonstrated that exogenous glial cell line-derived neurotrophic factor (GDNF) induces histological and functional protection of photoreceptors in the retinal degeneration (rd1) mouse model.
Neveux, N +4 more
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, 1987 We have identified a second Drosophila opsin gene, Rh4, which is expressed specifically in the ultraviolet-sensitive R7 photoreceptor cells. The two R7 opsins, Rh3 and Rh4, are expressed in nonoverlapping subsets of R7 cells.
G Rubin, K Jones, C Zuker, C Montell
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Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency
Frontiers in Behavioral Neuroscience, 2018 The retina has an intrinsic circadian clock, but the importance of this clock for vision is unknown. Zebrafish offer many advantages for studying vertebrate vision and circadian rhythm. Here, we explored the role of zebrafish per2, a light-regulated gene,
Deng-feng Huang +7 more
doaj +1 more source
The role of Xenopus Rx-L in photoreceptor cell determination.
, 2009 Members of the Rx (retinal homeobox) gene family play vital roles during eye development. In Xenopus, as in most other vertebrates, two Rx-type genes have been described.
Hollemann, Thomas +2 more
core +1 more source
Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179 [PDF]
, 2015 The rd1 mouse with a mutation in the Pde6b gene was the first strain of mice identified with a retinal degeneration. However, AAV-mediated gene supplementation of rd1 mice only results in structural preservation of photoreceptors, and restoration of the ...
Bainbridge, James W.B. +35 more
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A Study of Horizontal Cell-Photoreceptor Interaction in the Frog Retina Using a Randomly Modulated Stimulus [PDF]
, 1981 The intracellular responses of frog horizontal cells and photoreceptors to conventional and randomly modulated stimuli were recorded by intracellular probing using glass micropipettes.
Melton, Ronald Benjamin
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Distribution of guanylate cyclase within photoreceptor outer segments [PDF]
application/pdfGuanylate cyclases play an essential role in the recovery of vertebrate photoreceptor cells after light activation. Here, we have investigated how one such guanylate cyclase, RetGC-1, is distributed within light- and dark-adapted rod ...
WILLIAMS, David S. +6 more
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P2X7 Receptor Modulation of Visual Responses in the Retina [PDF]
, 2015 Adenosine 5’ triphosphate (ATP)-gated P2X7 receptors (P2X7Rs) are known to act as conduits for photoreceptor and retinal ganglion cell (RGC) damage, consequences of various neurodegenerative conditions within the visual pathway. Growing evidence supports
Chavda, S
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