Results 81 to 90 of about 4,900,943 (176)

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

PDE4DIP/Myomegalin as a Golgi–Centrosome Scaffold in Compartmentalized Signaling, Microtubule Organization, and Disease‐Associated Pathway Remodeling

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT PDE4DIP/Myomegalin was originally identified as a Golgi‐ and centrosome‐associated protein that interacts with phosphodiesterase 4D, but subsequent work has placed it within a broader network of organelle‐associated signaling and cytoskeletal regulation.
Cong Wang, Chunjing Bian, Zhe Wang, Tao Luo   +3 more
wiley   +1 more source

Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment

eLife, 2019
Animals detect light using opsin photopigments. Xenopsin, a recently classified subtype of opsin, challenges our views on opsin and photoreceptor evolution.
Kate A Rawlinson, Francois Lapraz, Edward R Ballister, Mark Terasaki, Jessica Rodgers, Richard J McDowell, Johannes Girstmair, Katharine E Criswell, Miklos Boldogkoi, Fraser Simpson, David Goulding, Claire Cormie, Brian Hall, Robert J Lucas, Maximilian J Telford   +14 more
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, Volume 83, Issue 10, Page 779-794, October 2026.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Light-modulated stem cells in the camera-type eye of an annelid model for adult brain plasticity

Nature Communications
Camera-type eyes in vertebrates and cephalopods are striking examples of parallel evolution of a complex structure. While comparisons have focused on these two groups, camera-type eyes with likely high functionality are also found in other invertebrate ...
Nadja Milivojev, Federico Scaramuzza, Pedro Ozório Brum, Camila L. Velastegui Gamboa, Gabriele Andreatta, Florian Raible, Kristin Tessmar-Raible   +6 more
doaj   +1 more source

A Biomimetic Model of the Outer Plexiform Layer by Incorporating Memristive Devices [PDF]

, 2011
In this paper we present a biorealistic model for the first part of the early vision processing by incorporating memristive nanodevices. The architecture of the proposed network is based on the organisation and functioning of the outer plexiform layer ...
Christofer Toumazou, Roska, Tamas, Gelencser, Andras, Themistoklis Prodromakis, Tamas Roska, Prodromakis, Themistoklis, Andras Gelencser, Toumazou, Christofer, Toumazou, C., Prodromakis, T., Roska, T., Gelencser, A.   +11 more
core   +1 more source

Functional analysis of A 5' untranslated variant in rhodopsin : implications for the retinitis pigmentosa phenotype [PDF]

, 2011
Retinitis Pigmentosa (RP) is a group of heterogeneous retinal degenerative diseases that predominantly affect rod photoreceptor cells. Symptoms include night blindness and gradual peripheral vision loss, which progresses to a complete loss of vision ...
Akinyi, Maureen Veronica
core   +1 more source

Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina

Scientific Reports, 2017
In the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (DAC). DAC activity is stimulated by rods, cones, and melanopsin-expressing intrinsically photosensitive retinal ...
Xiwu Zhao, Kwoon Y. Wong, Dao-Qi Zhang
doaj   +1 more source

Physiological Postnatal Neurogenesis, Development, and Maturation in the Regenerable Retina

Journal of Comparative Neurology, Volume 534, Issue 10, October 2026.
Retinal structural remodeling from hatchlings to preadults in axolotls involves neurogenesis, cell redistribution, increased expression of photopsins and connexins, and enhanced inhibitory regulation. The peripheral retina of young animals possesses more columnar undifferentiated cells, resembling the columnar DCX‐positive progenitor cells in the ...
Vivian Y. Pang, Wenhui Zhong, Zhuo Yang, Samuel Wu, Ji‐Jie Pang   +4 more
wiley   +1 more source

Neurotransmitter modulation of extracellular H+ fluxes from isolated retinal horizontal cells of the skate

, 2004
Self-referencing H+-selective microelectrodes were used to measure extracellular H+ fluxes from horizontal cells isolated from the skate retina. A standing H+ flux was detected from quiescent cells, indicating a higher concentration of free hydrogen ions
Verzi, Michael P., Birnbaum, Andrea D., Yamoah, Ebenezer N., Molina, Anthony J.A, Hammar, Katherine, Malchow, Robert Paul, Smith, Peter J.S.   +6 more
core   +1 more source