Results 11 to 20 of about 64,303 (289)

Histamine Recycling Is Mediated by CarT, a Carcinine Transporter in Drosophila Photoreceptors. [PDF]

PLoS Genetics, 2015
Histamine is an important chemical messenger that regulates multiple physiological processes in both vertebrate and invertebrate animals. Even so, how glial cells and neurons recycle histamine remains to be elucidated.
Ying Xu, Futing An, Jolanta A Borycz, Janusz Borycz, Ian A Meinertzhagen, Tao Wang   +5 more
doaj   +1 more source

Pineal photoreceptor cells are required for maintaining the circadian rhythms of behavioral visual sensitivity in zebrafish.

PLoS ONE, 2012
In non-mammalian vertebrates, the pineal gland functions as the central pacemaker that regulates the circadian rhythms of animal behavior and physiology. We generated a transgenic zebrafish line [Tg(Gnat2:gal4-VP16/UAS:nfsB-mCherry)] in which the E. coli
Xinle Li, Jake Montgomery, Wesley Cheng, Jung Hyun Noh, David R Hyde, Lei Li   +5 more
doaj   +1 more source

Using electroretinograms and multi-model inference to identify spectral classes of photoreceptors and relative opsin expression levels [PDF]

PeerJ, 2017
Understanding how individual photoreceptor cells factor in the spectral sensitivity of a visual system is essential to explain how they contribute to the visual ecology of the animal in question.
Nicolas Lessios
doaj   +2 more sources

Role of Oxidative Stress in Retinal Photoreceptor Cell Death in N-Methyl-N-nitrosourea–Treated Mice

Journal of Pharmacological Sciences, 2012
This study aimed to investigate whether oxidative stress contributes to retinal cell death in a mouse model of photoreceptor degeneration induced by N-methyl-N-nitrosourea (MNU).
Kazuhiro Tsuruma, Mika Yamauchi, Yuta Inokuchi, Sou Sugitani, Masamitsu Shimazawa, Hideaki Hara   +5 more
doaj   +1 more source

In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells

Biology Open, 2016
Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells.
Yukari Komuta, Toshiyuki Ishii, Makoto Kaneda, Yasuji Ueda, Kiyoko Miyamoto, Masashi Toyoda, Akihiro Umezawa, Yuko Seko   +7 more
doaj   +1 more source

Differentiation of human olfactory mucosa mesenchymal stem cells into photoreceptor cells in vitro [PDF]

International Journal of Ophthalmology, 2017
AIM: To investigate whether the human olfactory mucosa mesenchymal stem cells (OM-MSCs) can differentiate into photoreceptor cells in vitro. METHODS: Through the olfactory mucosa adherent method, olfactory mucosa was isolated, cultured and identified in
Wen Lu, Da Duan, Zacharia Ackbarkhan, Ming Lu, Min-Li Huang   +4 more
doaj   +1 more source

Insights into the evolutionary origin of the pineal color discrimination mechanism from the river lamprey

BMC Biology, 2021
Background Pineal-related organs in cyclostomes, teleosts, amphibians, and reptiles exhibit color opponency, generating antagonistic neural responses to different wavelengths of light and thereby sensory information about its “color”.
Seiji Wada, Emi Kawano-Yamashita, Tomohiro Sugihara, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita   +5 more
doaj   +1 more source

Alterations in kainate receptor and TRPM1 localization in bipolar cells after retinal photoreceptor degeneration

Frontiers in Cellular Neuroscience, 2015
Photoreceptor degeneration differentially impacts glutamatergic signaling in downstream On and Off bipolar cells. In rodent models, photoreceptor degeneration leads to loss of glutamatergic signaling in On bipolar cells, whereas Off bipolar cells appear ...
Jacqueline eGayet-Primo, Theresa ePuthussery   +1 more
doaj   +1 more source

Three distinct roles for notch in Drosophila R7 photoreceptor specification. [PDF]

PLoS Biology, 2011
Receptor tyrosine kinases (RTKs) and Notch (N) proteins are different types of transmembrane receptors that transduce extracellular signals and control cell fate.
Andrew Tomlinson, Yannis Emmanuel Mavromatakis, Gary Struhl   +2 more
doaj   +1 more source

Chemically-induced photoreceptor degeneration and protection in mouse iPSC-derived three-dimensional retinal organoids

Stem Cell Research, 2017
Induced pluripotent stem cells (iPSCs), which can be differentiated into various tissues and cell types, have been used for clinical research and disease modeling.
Shin-ichiro Ito, Akishi Onishi, Masayo Takahashi   +2 more
doaj   +1 more source