Results 21 to 30 of about 64,303 (289)
Photoreceptor cells constitutively express functional TLR4 [PDF]
Journal of Neuroimmunology, 2011 Toll-like receptor 4 (TLR4) is expressed on a number of cells including neurons in the brain. However, it has yet to be determined if TLR4 is expressed on photoreceptor cells in the retina. In this report, we examined primary photoreceptor cells and an established photoreceptor cell line (661W). We found that functional TLR4 is constitutively expressed
Zhidan, Tu +7 more
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Phototransduction in ganglion-cell photoreceptors [PDF]
Pflügers Archiv - European Journal of Physiology, 2007 A third class of photoreceptors has recently been identified in the mammalian retina. They are a rare cell type within the class of ganglion cells, which are the output cells of the retina. These intrinsically photosensitive retinal ganglion cells support a variety of physiological responses to daylight, including synchronization of circadian rhythms ...
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STEREOLOGY AND SOME STRUCTURAL CORRELATES OF RETINAL AND PHOTORECEPTOR CELL FUNCTION
Image Analysis and Stereology, 2011 The retina is the part of the eye which detects light, transduces it into nerve impulses and plays a significant role in visual perception. Sensitivity to light is multi-factorial and depends on the properties of photopigment molecules, their synthesis ...
Terry M Mayhew
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Photoreceptor cell fate specification in vertebrates [PDF]
Development, 2015 Photoreceptors – the light-sensitive cells in the vertebrate retina – have been extremely well-characterized with regards to their biochemistry, cell biology and physiology. They therefore provide an excellent model for exploring the factors and mechanisms that drive neural progenitors into a differentiated cell fate in the nervous system. As a result,
Joseph A, Brzezinski, Thomas A, Reh
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Role of microglial cells in photoreceptor degeneration
Neural Regeneration Research, 2019 Inherited photoreceptor degeneration in humans constitutes a major cause of irreversible blindness in the world. They comprise various diseases, but retinitis pigmentosa is the most frequently observed. Retinitis pigmentosa is commonly limited to the eye,
Johnny Di Pierdomenico +4 more
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Localization of acetylcholine-related molecules in the retina: implication of the communication from photoreceptor to retinal pigment epithelium. [PDF]
PLoS ONE, 2012 It has been long speculated that specific signals are transmitted from photoreceptors to the retinal pigment epithelium (RPE). However, such signals have not been identified.
Hidetaka Matsumoto +10 more
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Arrestins expressed in killifish photoreceptor cells [PDF]
FEBS Letters, 1997 Two kinds of cDNA fragments (KfhArr‐R and KfhArr‐C) encoding the putative arrestins of killifish,Oryzias latipes, were isolated. The distributions of these transcripts were investigated by in situ hybridization, and it was demonstrated that KfhArr‐R and KfhArr‐C are expressed in, respectively, rod and all four types of cone cells.
Hisatomi, Osamu +3 more
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Rapamycin Improved Retinal Function and Morphology in a Mouse Model of Retinal Degeneration
Frontiers in Neuroscience, 2022 The retina is an important visual organ, which is responsible for receiving light signals and transmitting them to the optic nerve center step by step.
Meng Zhao +7 more
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Stem Cells International, 2012 Purpose. Transplantation of stem, progenitor, or precursor cells has resulted in photoreceptor replacement and evidence of functional efficacy in rodent models of retinal degeneration.
H. Klassen +8 more
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eLife, 2013 Next-generation and Sanger sequencing were combined to identify disease-causing USH2A mutations in an adult patient with autosomal recessive RP. Induced pluripotent stem cells (iPSCs), generated from the patient’s keratinocytes, were differentiated into ...
Budd A Tucker +9 more
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