Results 41 to 50 of about 20,821 (225)

Exploiting Device Mismatch in Neuromorphic VLSI Systems to Implement Axonal Delays [PDF]

open access: yes, 2012
Sheik S, Chicca E, Indiveri G. Exploiting Device Mismatch in Neuromorphic VLSI Systems to Implement Axonal Delays. Presented at the International Joint Conference on Neural Networks (IJCNN), Brisbane, Australia.Axonal delays are used in neural ...
Chicca, Elisabetta   +2 more
core   +4 more sources

Long-term rearrangement of retinal structures in a novel mutation of X-linked retinoschisis [PDF]

open access: yes, 2017
The aim of the present study was to report a novel mutation in the retinoschisin 1 (RS1) gene in a Caucasian family affected by X-linked juvenile retinoschisis (XLRS) and to describe the long-term modification of retinal structure.
Colavito, Davide   +7 more
core   +1 more source

Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. [PDF]

open access: yes, 2017
The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could ...
Angueyra, Juan M   +9 more
core   +1 more source

BRP-170 and BRP190 isoforms of Bruchpilot protein differentially contribute to the frequency of synapses and synaptic circadian plasticity in the visual system of Drosophila [PDF]

open access: yes, 2015
In the first optic neuropil (lamina) of the optic lobe of Drosophila melanogaster, two classes of synapses, tetrad and feedback, show daily rhythms in the number and size of presynaptic profiles examined at the level of transmission electron microscopy ...
Görlich, Alicja   +3 more
core   +6 more sources

Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration

open access: yesiScience, 2021
Summary: The group of retinal degenerations, retinitis pigmentosa (RP), comprises more than 150 genetic abnormalities affecting photoreceptors. Finding degenerative pathways common to all genetic abnormalities may allow general treatment such as ...
Zhongjie Fu   +13 more
doaj   +1 more source

TRANSGENIC STRATEGY FOR IDENTIFYING SYNAPTIC CONNECTIONS IN MICE BY FLUORESCENCE COMPLEMENTATION (GRASP)

open access: yesFrontiers in Molecular Neuroscience, 2012
In the "GFP reconstitution across synaptic partners" (GRASP) method, non-fluorescent fragments of GFP are expressed in two different neurons; the fragments self-assemble at synapses between the two to form a fluorophore. GRASP has proven useful
Masahito eYamagata, Joshua R Sanes
doaj   +1 more source

Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina. [PDF]

open access: yesPLoS ONE, 2009
The Synaptic Vesicle Protein 2 (SV2) family of transporter-like proteins is expressed exclusively in vesicles that undergo calcium-regulated exocytosis. Of the three isoforms expressed in mammals, SV2B is the most divergent.
Catherine W Morgans   +6 more
doaj   +1 more source

Dual-Cell Patch-Clamp Recording Revealed a Mechanism for a Ribbon Synapse to Process Both Digital and Analog Inputs and Outputs

open access: yesFrontiers in Cellular Neuroscience, 2021
A chemical synapse is either an action potential (AP) synapse or a graded potential (GP) synapse but not both. This study investigated how signals passed the glutamatergic synapse between the rod photoreceptor and its postsynaptic hyperpolarizing bipolar
Ji-Jie Pang, Fan Gao, Samuel M. Wu
doaj   +1 more source

Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]

open access: yes, 2017
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás   +3 more
core   +1 more source

Rab3A Mediates Vesicle Delivery at Photoreceptor Ribbon Synapses [PDF]

open access: yesThe Journal of Neuroscience, 2012
Rab3A is a synaptic vesicle-associated protein found throughout the nervous system, but its precise function is unknown. Genetic knock-out studies show that Rab3A is not necessary for vesicular release or replenishment at conventional synapses in the brain.
Miao, Tian   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy