Results 121 to 130 of about 32,454 (332)

Bioprinted Organoids: An Innovative Engine in Biomedicine

Advanced Science, EarlyView.
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li, Kai Li, Cheng Zhang, Yingying Zhao, Yiyuan Guo, Jia He, Shiyuan Chang, Xinyi Fang, Kaizheng Liu, Pingping Zhu, Zhenzhen Chen, Changshun Ruan   +11 more
wiley   +1 more source

Assessment of the potential genotoxicity and phototoxicity of triazine UV filters

Journal of Dermatologic Science and Cosmetic Technology
Background: Ethylhexyl triazone (EHT) and diethylhexyl butamido triazone (HEB) both belong to the recently developed class of triazine ultraviolet filters. However, their toxicity profiles remain unclear. Objective: To assess the genotoxic and phototoxic
Yilian Wei, Meng Xiang, Jinyu Dong, Zhigang Wang, Xuan Wang, Hao Liu, Jianjun Liu, Wenli Xu, Jie Li, Yibei Zhan   +9 more
doaj  

Unveiling Exciton‐Plasmon Polariton Coupling Regions via Polarization‐Enhanced Optical Nanoscopy

Advanced Science, EarlyView.
Polarization‐enhanced single‐molecule localization microscopy, utilizing a liquid crystal variable retarder (LCVR), actively controls the on‐off intensity modulation of fluorophores. This active intensity modulation improves the localization accuracy of the point spread function (PSF), enabling high‐contrast super‐resolution imaging with significantly ...
Bin Chan Joo, Dong Hee Park, Kyu Ri Choi, Yeon Ui Lee   +3 more
wiley   +1 more source

Repeated exposure to low doses of light induces retinal damage in vivo in a wavelength-dependent manner

Ecotoxicology and Environmental Safety
The exposure of the general population to artificial light at night has dramatically increased in recent decades. Current standards for domestic lighting are based on acute exposure to light and consider blue wavelengths to be responsible for ...
Anaïs Françon, Laurent Jonet, Francine Behar-Cohen, Alicia Torriglia   +3 more
doaj  

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

Advanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma, Yihao Zhang, Junkai Cai, Baotong Ding, Yang Jiao, Chunying Duan   +5 more
wiley   +1 more source

Water‐Soluble Molecular Wires for Membrane Potential Imaging

Angewandte Chemie, EarlyView.
Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib, Margret A. Fye, Keita Uchida, Ana L. Obaid, Thomas Troxler, Dylan Valente, Brian M. Salzberg, Benjamin Prosser, Irina N. Kaverina, Sergei A. Vinogradov   +9 more
wiley   +2 more sources

Two Small Molecule Drugs with Topical Applications, Diflunisal and Naphazoline, and Their Potentially Toxic Photodegradants: Analysis by Chemical and Biological Methods

Molecules
Because of their topical application in patients and meaningful UV/VIS absorptive properties, the degradation and potential toxicity under irradiation of diflunisal (DIF) and naphazoline (NAF) were studied.
Karolina Lejwoda, Anna Gumieniczek, Agata Filip, Beata Naumczuk   +3 more
doaj   +1 more source

Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe

Advanced Science, EarlyView.
Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou, Hao Sha, Shengjie Fu, Guannan Liu, Jinbei Wei, Chenguang Wang, Shangguo Hou, Geyu Lu   +7 more
wiley   +1 more source

A Genetically Encoded Homocysteine Precursor to Probe Protein Active Sites and to Addict Escherichia coli to a Noncanonical Amino Acid Directly Involved in Catalysis

Angewandte Chemie, EarlyView.
A new genetically encoded amino acid is chemically converted into homocysteine (Hcy) under mild conditions to probe and to activate protein active sites. Surprisingly, Hcy can replace cysteine or serine residues in several enzymes. Its potential for a widespread use in proteins is further underlined by rendering Escherichia coli dependent on Hcy ...
Clara Dunker, Henning D. Mootz
wiley   +2 more sources

Synergy between Defects and Lattice Distortion Drives Self‐Powered Elastico‐Near‐Infrared Mechanoluminescence in Cr3+‐Doped Spinel Oxides

Advanced Science, EarlyView.
This work demonstrates crystal lattice tailoring and defect modulation to engineer a Cr3+‐activated cubic spinel oxide, where strategic introduction of Cr3+ into octahedral Al3+/Li+ sites drives efficient NIR‐ML through a non‐trap‐based mechanism. Abstract Elastico‐mechanoluminescence (ML) enables unique force‐to‐light transduction for applications in ...
Yao Xiao, Kang Chen, Mingzi Sun, Puxian Xiong, Bolong Huang, Yongsheng Sun, Dongdan Chen, Jiulin Gan, Zhongmin Yang   +8 more
wiley   +1 more source