Results 121 to 130 of about 3,532 (155)

Chemogenetic stimulation of phrenic motor output and diaphragm activity. [PDF]

open access: yesElife
Benevides ES   +6 more
europepmc   +1 more source

Anatomy, Imaging, and Clinical Significance of the Cervicothoracic (Stellate) Ganglion. [PDF]

open access: yesDiagnostics (Basel)
Rusu MC   +6 more
europepmc   +1 more source

Phrenic motor neuron adenosine 2A receptors elicit phrenic motor facilitation [PDF]

open access: yesJournal of Physiology, 2018
Key points Although adenosine 2A (A2A) receptor activation triggers specific cell signalling cascades, the ensuing physiological outcomes depend on the specific cell type expressing these receptors. Cervical spinal adenosine 2A (A2A) receptor activation elicits a prolonged facilitation in phrenic nerve activity, which was nearly abolished following ...
Yasin B Seven   +2 more
exaly   +3 more sources

Glutamatergic input varies with phrenic motor neuron size [PDF]

open access: yesJournal of Neurophysiology, 2019
Like all skeletal muscles, the diaphragm muscle accomplishes a range of motor behaviors by recruiting different motor unit types in an orderly fashion. Recruitment of phrenic motor neurons (PhMNs) is generally assumed to be based primarily on the intrinsic properties of PhMNs with an equal distribution of descending excitatory inputs to all PhMNs ...
Sabhya Rana   +2 more
exaly   +3 more sources

Postnatal Phrenic Motor Neuron and Diaphragm Maturation in the Mouse

The FASEB Journal, 2022
In rats, there is a strong association between the expansion of phrenic motor neuron (PhMN) size (from ~21‐28 days postnatal), the emergence of mature diaphragm muscle (DIAm) myosin heavy chain (MyHC 2X and MyHC 2B ) isoform expression, alongside the ...
Joline E. Brandenburg   +3 more
openaire   +1 more source

A Model of the Rat Phrenic Motor Neuron

IEEE Transactions on Biomedical Engineering, 2002
We have developed a model for the rat phrenic motor neuron (PMN) that robustly replicates many experimentally observed behaviors of PMNs in response to pharmacological, ionic, and electrical perturbations using a single set of parameters. Our model suggests that the after-depolarization (ADP) response seen in action potentials is a result of the slow ...
Behrang Amini   +3 more
openaire   +2 more sources

Phrenic motor neuron survival below cervical spinal cord hemisection

Experimental Neurology, 2021
Cervical spinal cord injury (cSCI) severs bulbospinal projections to respiratory motor neurons, paralyzing respiratory muscles below the injury. C2 spinal hemisection (C2Hx) is a model of cSCI often used to study spontaneous and induced plasticity and breathing recovery post-injury.
Latoya L, Allen   +8 more
openaire   +2 more sources

The ultrastructure and synaptic architecture of phrenic motor neurons in the spinal cord of the adult rat

Journal of Neurocytology, 1984
Although light microscopic studies have analysed phrenic motor neurons in several different species, there has never been an ultrastructural investigation of identified phrenic motor neurons. In addition, electrophysiological studies have raised questions relating to the function of phrenic motor neurons which may be answered only by direct electron ...
Harry G Goshgarian, JOSÉ A Rafols
exaly   +3 more sources

Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size

Molecular and Cellular Neuroscience, 2023
Brain derived neurotrophic factor (BDNF) signalling through its high-affinity tropomyosin receptor kinase B (TrkB) is known to have potent effects on motor neuron survival and morphology during development and in neurodegenerative diseases. Here, we employed a novel 1NMPP1 sensitive TrkBF616 rat model to evaluate the effect of 14 days inhibition of ...
Matthew J, Fogarty   +3 more
openaire   +2 more sources

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