Results 121 to 130 of about 3,532 (155)
Chemogenetic stimulation of phrenic motor output and diaphragm activity. [PDF]
Benevides ES +6 more
europepmc +1 more source
Adenosine A2A receptor signaling in neuroinflammation, glial modulation, and mechanisms associated with chronic pain. [PDF]
Barros CA +4 more
europepmc +1 more source
Anatomy, Imaging, and Clinical Significance of the Cervicothoracic (Stellate) Ganglion. [PDF]
Rusu MC +6 more
europepmc +1 more source
Phrenic motor neuron adenosine 2A receptors elicit phrenic motor facilitation [PDF]
Key points Although adenosine 2A (A2A) receptor activation triggers specific cell signalling cascades, the ensuing physiological outcomes depend on the specific cell type expressing these receptors. Cervical spinal adenosine 2A (A2A) receptor activation elicits a prolonged facilitation in phrenic nerve activity, which was nearly abolished following ...
Yasin B Seven +2 more
exaly +3 more sources
Glutamatergic input varies with phrenic motor neuron size [PDF]
Like all skeletal muscles, the diaphragm muscle accomplishes a range of motor behaviors by recruiting different motor unit types in an orderly fashion. Recruitment of phrenic motor neurons (PhMNs) is generally assumed to be based primarily on the intrinsic properties of PhMNs with an equal distribution of descending excitatory inputs to all PhMNs ...
Sabhya Rana +2 more
exaly +3 more sources
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Postnatal Phrenic Motor Neuron and Diaphragm Maturation in the Mouse
The FASEB Journal, 2022In rats, there is a strong association between the expansion of phrenic motor neuron (PhMN) size (from ~21‐28 days postnatal), the emergence of mature diaphragm muscle (DIAm) myosin heavy chain (MyHC 2X and MyHC 2B ) isoform expression, alongside the ...
Joline E. Brandenburg +3 more
openaire +1 more source
A Model of the Rat Phrenic Motor Neuron
IEEE Transactions on Biomedical Engineering, 2002We have developed a model for the rat phrenic motor neuron (PMN) that robustly replicates many experimentally observed behaviors of PMNs in response to pharmacological, ionic, and electrical perturbations using a single set of parameters. Our model suggests that the after-depolarization (ADP) response seen in action potentials is a result of the slow ...
Behrang Amini +3 more
openaire +2 more sources
Phrenic motor neuron survival below cervical spinal cord hemisection
Experimental Neurology, 2021Cervical spinal cord injury (cSCI) severs bulbospinal projections to respiratory motor neurons, paralyzing respiratory muscles below the injury. C2 spinal hemisection (C2Hx) is a model of cSCI often used to study spontaneous and induced plasticity and breathing recovery post-injury.
Latoya L, Allen +8 more
openaire +2 more sources
Journal of Neurocytology, 1984
Although light microscopic studies have analysed phrenic motor neurons in several different species, there has never been an ultrastructural investigation of identified phrenic motor neurons. In addition, electrophysiological studies have raised questions relating to the function of phrenic motor neurons which may be answered only by direct electron ...
Harry G Goshgarian, JOSÉ A Rafols
exaly +3 more sources
Although light microscopic studies have analysed phrenic motor neurons in several different species, there has never been an ultrastructural investigation of identified phrenic motor neurons. In addition, electrophysiological studies have raised questions relating to the function of phrenic motor neurons which may be answered only by direct electron ...
Harry G Goshgarian, JOSÉ A Rafols
exaly +3 more sources
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size
Molecular and Cellular Neuroscience, 2023Brain derived neurotrophic factor (BDNF) signalling through its high-affinity tropomyosin receptor kinase B (TrkB) is known to have potent effects on motor neuron survival and morphology during development and in neurodegenerative diseases. Here, we employed a novel 1NMPP1 sensitive TrkBF616 rat model to evaluate the effect of 14 days inhibition of ...
Matthew J, Fogarty +3 more
openaire +2 more sources

