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Physcion and Physcion 8-O-β-D-glucopyranoside: Natural Anthraquinones with Potential Anticancer Activities [PDF]

open access: yesCurrent Drug Targets, 2021
Nature has provided prodigious reservoirs of pharmacologically active compounds for drug development since times. Physcion and physcion 8-O-β-D-glucopyranoside (PG) are bioactive natural anthraquinones which exert anti-inflammatory and anticancer properties with minimum or no adverse effects.
Ammara Riaz   +2 more
exaly   +5 more sources
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Microbial production of the plant-derived fungicide physcion

Metabolic Engineering, 2022
Physcion is a characteristic component of the traditional herb rhubarb with diverse pharmacological activities that has been commercially approved as an herbal fungicide. Nevertheless, its extremely low contents, costly purification procedure and geographically restricted planting severely hinder its application. Here, a cell factory was constructed in
Xuefeng Lu, Feifei Qi, Yingying Xue
exaly   +3 more sources

Physcion, a novel anthraquinone derivative against Chlamydia psittaci infection

open access: yesVeterinary Microbiology, 2023
Physcion, a natural anthraquinone derivative, has been reported to exert remarkable antibacterial activities against Staphylococcus aureus,Staphylococcus epidermidis and Pseudomonas aeruginosa. However, it is not fully illustrated as anti-Chlamydia substance.
Cheng He
exaly   +3 more sources

Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics

Chemico-Biological Interactions, 2019
Anthraquinones constitute an important class of natural and synthetic compounds with a broad scope of pharmacological including anti-bacterial, antioxidant, laxative, anti-tumor and other activities. Physcion and physcion 8-O-β-glucopyranoside (PG) are common anthraquinones existed in various plants.
Nai-Hong Chen   +2 more
exaly   +3 more sources

Mass Spectral Studies of Physcion

open access: yesZeitschrift Fur Naturforschung - Section C Journal of Biosciences, 1974
Pahup Singh, Krishna C Joshi
exaly   +3 more sources

Physcion and dihydrocarinatin from Aristolochia birostris

Biochemical Systematics and Ecology, 2003
J M Barbosa-Filho
exaly   +2 more sources

Physcion-Matured Dendritic Cells Induce the Differentiation of Th1 Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
In addition to their use as colorants, anthraquinone derivatives have numerous medical applications, for example, as antibacterial and antiinflammatory agents. We confirmed that physcion (an anthraquinone derivative) induces TNF-alpha production by macrophages and increased the expressions of surface molecules (CD40, CD80, and CD86) and major ...
Sung-Tae Yee
exaly   +3 more sources

A new polymorph of physcion

Acta Crystallographica Section C Crystal Structure Communications, 2012
The structure of the title compound, 7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione, C16H12O5, was originally reported by Ulickýet al.[Acta Cryst.(1991). C47, 1879–1881] in the space groupP212121[polymorph (Io)]. The new polymorph, (Im), crystallizes in the space groupP21/c.
Henning, Hopf   +4 more
openaire   +2 more sources

Mining an O-methyltransferase for de novo biosynthesis of physcion in Aspergillus nidulans

Applied Microbiology and Biotechnology, 2023
Physcion is one of natural anthraquinones, registered as a novel plant-derived fungicide due to its excellent prevention of plant disease. However, the current production of physcion via plant extraction limits its yield promotion and application.
Yongpeng Yao   +4 more
openaire   +2 more sources

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