Results 51 to 60 of about 4,616,743 (362)

Physical fitness training for stroke patients [PDF]

Stroke, 2001
Physical fitness is low after stroke. It is unknown whether improving physical fitness after stroke reduces disability.To determine whether fitness training (cardiorespiratory or strength, or both) after stroke reduces death, dependence and disability.
Brazzelli, Miriam, Saunders, David H, Greig, Carolyn A, Mead, Gillian E   +3 more
openaire   +10 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Endurance exercise resistance to lipotoxic cardiomyopathy is associated with cardiac NAD+/dSIR2/PGC-1α pathway activation in old Drosophila

Biology Open, 2019
Lipotoxic cardiomyopathy is caused by excessive lipid accumulation in myocardial cells and it is a form of cardiac dysfunction. Cardiac PGC-1α overexpression prevents lipotoxic cardiomyopathy induced by a high-fat diet (HFD).
Deng-Tai Wen, Lan Zheng, Jin-xiu Li, Dan Cheng, Yang Liu, Kai Lu, Wen-qi Hou   +6 more
doaj   +1 more source

PHYSICAL FITNESS AND INCIDENT HYPERTENSION: THE FIT PROJECT

Journal of the American College of Cardiology, 2014
Increased physical fitness plays a role in cardiovascular disease prevention. We hypothesized that increased fitness would be inversely associated with incident hypertension (HTN). We examined the association of fitness with incident HTN in 22,109 participants from The FIT (Henry Ford ...
John Schairer, Steven K Keteyian, Michael J. Blaha, Seamus P. Whelton, Steven P. Jones, Roger S. Blumenthal, Stephen P. Juraschek, Mouaz Al-Mallah   +7 more
openaire   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Prevalence of physical fitness in Chinese school-aged children: Findings from the 2016 Physical Activity and Fitness in China—The Youth Study

Journal of Sport and Health Science, 2017
Purpose: This study was to present the 2016 prevalence estimates of Chinese school-aged children meeting physical fitness standards and to examine differences by sex and residence locales in children who did not meet fitness standards.
Zheng Zhu, Yang Yang, Zhenxing Kong, Yimin Zhang, Jie Zhuang   +4 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Systematic Review of Changes and Recovery in Physical Function and Fitness After Severe Acute Respiratory Syndrome–Related Coronavirus Infection: Implications for COVID-19 Rehabilitation

Physical Therapy, 2020
Objectives 1) Compare physical function and fitness outcomes in people infected with SARS-CoV to healthy controls; 2) quantify the recovery of physical function and fitness following SARS-CoV infection; 3) determine the effects of exercise following SARS-
Scott Rooney, Amy Webster, L. Paul
semanticscholar   +1 more source

Loss of popdc3 Impairs Mitochondrial Function and Causes Skeletal Muscle Atrophy and Reduced Swimming Ability in Zebrafish

Journal of Cachexia, Sarcopenia and Muscle
Background The Popeye domain containing 3 (POPDC3) protein is essential for the maintenance of skeletal muscle homeostasis. POPDC3 is a pathogenic variant gene of limb‐girdle muscular dystrophy (LGMD), and its variants lead to LGMDR26.
Chen‐Chen Sun, Zhang‐Lin Chen, Dong Yang, Jiang‐Ling Xiao, Xiang‐Tao Chen, Xi‐Yang Peng, Xiu‐Shan Wu, Chang‐Fa Tang   +7 more
doaj   +1 more source

The Impact of Sport-Specific Practice on Health-Related Physical Fitness Components in Young Water Polo and Volleyball Athletes

Applied Sciences
Physical fitness (PF) has been identified as a critical health marker in youth and is significantly influenced by environmental factors, such as the specificity of training involved in different sports.
Francesco Sgrò, Michele Barca, Federico Mollame, Francesca Orofino, Antonella Quinto, David Stodden   +5 more
doaj   +1 more source