Results 51 to 60 of about 200,268 (247)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

The Impact of Sport-Specific Practice on Health-Related Physical Fitness Components in Young Water Polo and Volleyball Athletes

Applied Sciences
Physical fitness (PF) has been identified as a critical health marker in youth and is significantly influenced by environmental factors, such as the specificity of training involved in different sports.
Francesco Sgrò, Michele Barca, Federico Mollame, Francesca Orofino, Antonella Quinto, David Stodden   +5 more
doaj   +1 more source

Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck, Jan Voth, Noëmi Gmahl, Konstantin Jendretzky, Niklas Huntemann, Noah M. Werner, Linea Schmidt, Menekse Oeztuerk, Paula Quint, Christina B. Schroeter, Hans Peter Hartung, Thomas Skripuletz, Gerd Meyer zu Hörste, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki   +15 more
wiley   +1 more source

The Degree of Influence of Daily Physical Activity on Quality of Life in Type 2 Diabetics

Frontiers in Psychology, 2020
Objectives: This study mainly explored the degree of influence of daily physical activity (PA) on the quality of life (QoL) and then provided a basis for improving PA and QoL in patients with Type 2 diabetes mellitus (T2DM).Methods: Long International PA
Feng Zhang, Feng Zhang, Li Huang, Li Huang, Li Peng, Li Peng   +5 more
doaj   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Effects of Treadmill Exercise on Gut Microbiota in Alzheimer’s Disease Model Mice and Wild-Type Mice

Microorganisms
There is a growing body of research showing that Alzheimer’s disease (AD) is related to enteric dysbacteriosis. Exercise can be effective in alleviating AD, but the effects that exercise has on the gut microbiota in AD patients needs to be further ...
Zhe Zhao, Xingqing Wu, Wenfeng Liu, Lan Zheng, Changfa Tang   +4 more
doaj   +1 more source

The Influence of Sports Participation on Body Image, Self-Efficacy, and Self-Esteem in College Students

Frontiers in Psychology, 2020
ObjectivesThis study aimed to explore the relationship between body image, self-efficacy, self-esteem, and sports participation by gender, grade, and specialty and then to provide a reference for promoting participation in sports and physical activities ...
Yiyi Ouyang, Yiyi Ouyang, Kun Wang, Kun Wang, Tingran Zhang, Tingran Zhang, Li Peng, Li Peng, Gan Song, Gan Song, Jiong Luo, Jiong Luo   +11 more
doaj   +1 more source

Effects of Ageing in Physical Fitness

Occupational Medicine & Health Affairs, 2016
Ageing is a natural and inevitable process with degenerative changes in most of the physical, physiological and psychological functions. Furthermore, the ageing process has an impact on the physical of elderly people. Thus, the aim of this study is to provide to readers of information about effects of ageing and changes in physical fitness as
Ruiz-Montero, Pedro Jesús, Chiva-Bartoll, Oscar, Martín-Moya, Ricardo   +2 more
openaire   +3 more sources

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source