Results 31 to 40 of about 920,102 (313)
A New Frontier in Epilepsy: Novel Antiepileptogenic Drugs
Journal of Pharmacological Sciences, 2006 .: Epilepsy is a hetergenous syndrome characterized by recurrently and repeatedly occurring seizures. Although able to inhibit the epileptic seizures, the currently available antiepileptic drugs (AEDs) have no effects on epileptogenesis. Such AEDs should
Masashi Sasa
doaj +1 more source
Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications [PDF]
British Journal of Clinical Pharmacology, 2003 As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. It provides direct access to disease in the treatment of respiratory diseases, while providing an enormous surface area and a relatively low enzymatic, controlled environment for systemic
N R, Labiris, M B, Dolovich
openaire +2 more sources
Connexin-dependent neuroglial networking as a new therapeutic target [PDF]
, 2017 Astrocytes and neurons dynamically interact during physiological processes, and it is now widely accepted that they are both organized in plastic and tightly regulated networks.
Christian C. Naus +5 more
core +2 more sources
BioChemThe elderly population is growing worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, but their adverse events can pose significant risks. Different NSAID molecules can exhibit varying risk profiles.
Carolina Costa +5 more
doaj +1 more source
Nephroprotective Plants: A Review on the Use in Pre-Renal and Post-Renal Diseases
Plants, 2022 Kidney diseases are expected to become the fifth leading cause of death by 2040. Several physiological failures classified as pre-, intra-, and post-renal factors induce kidney damage.
Mario Adrián Tienda-Vázquez +7 more
doaj +1 more source
Leukotriene Receptor Antagonists and Related Compounds
Canadian Respiratory Journal, 1999 Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
doaj +1 more source
COUGH PHYTOTHERAPY IN CHILDREN
Педиатрическая фармакология, 2013 Cough is one of the most widespread causes of outpatient pediatrician’s visits. There has been a notable increase in the use of phytogenic drugs recently, including treatment of respiratory infections in children.
L. R. Selimzyanova +2 more
doaj +1 more source
On-Target Side Effects of Targeted Therapeutics of Cancer
Pathology and Oncology Research, 2022 The concept of precision medicine is based on the identification of hallmarks of cancer to exploit them as drug targets. The basic idea was that in this way the therapeutic modalities will be more effective and the side effects will be less.
József Tímár, Andrea Uhlyarik
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
PLoS ONE, 2022 Background and purpose CaV1.2 channels contribute to action potential upstroke in pacemaker cells, plateau potential in working myocytes, and initiate excitation-contraction coupling.
Ming Ren +8 more
doaj +2 more sources