Results 11 to 20 of about 31,417,318 (246)
A physiologically based pharmacokinetic model for ionic silver and silver nanoparticles [PDF]
International Journal of Nanomedicine, 2013 Gerald Bachler, Natalie von Goetz, Konrad Hungerbühler ETH Zurich, Institute for Chemical and Bioengineering, Zurich, Switzerland Abstract: Silver is a strong antibiotic that is increasingly incorporated into consumer products as a bulk, salt, or ...
Bachler G +2 more
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International Journal of Nanomedicine, 2016 Ulrika Carlander,1 Dingsheng Li,2 Olivier Jolliet,2 Claude Emond,3,4 Gunnar Johanson1 1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; 2Department of Environmental Health Sciences, School of Public Health, University of ...
Carlander U +4 more
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Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development [PDF]
ADMET and DMPK, 2019 Physiologically based pharmacokinetic (PBPK) modeling is a mechanistic or physiology based mathematical modeling technique which integrates the knowledge from both drug-based properties including physiochemical and biopharmaceutical properties and system
Abdul Naveed Shaik, Ansar Ali Khan
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Physiologically based pharmacokinetic (PBPK) model of chlorzoxazone
, 2023 This repository provides the chlorzoxazone physiologically based pharmacokinetic (PBPK) model. If you have any questions or problems please open an issue FundingMatthias König were supported by the Federal Ministry of Education and Research (BMBF ...
Küttner, Jonas, König, Matthias
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Physiologically based pharmacokinetic (PBPK) model of talinolol
, 2023 <p>This repository provides the talinolol physiologically based pharmacokinetic (PBPK) model.</p> <p>If you have any questions or problems please <a href="https://github.com/matthiaskoenig/talinolol-model/issues">open an issue</
Stemmer Mallol, Beatrice Amelie +1 more
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A minimal physiologically based pharmacokinetic model for high-dose methotrexate [PDF]
, 2021 Purpose: High-dose methotrexate (HDMTX) is administered for the treatment of a variety of malignant tumors. Wide intra- and inter-individual variabilities characterize the pharmacokinetics of MTX, which is mostly excreted renally.
Pesenti, G., Manca, D., Foppoli, M.
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Pharmaceutics, 2022 Pregnancy is associated with physiological changes that may affect drug pharmacokinetics (PKs). The aim of this study was to establish a maternal–fetal physiologically based pharmacokinetic (PBPK) model of oxcarbazepine (OXC) and its active metabolite ...
Lixia He +7 more
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Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies [PDF]
, 2015 Introduction: The pharmacokinetic properties of anti-infective drugs are a determinant part of treatment success. Pathogen replication is inhibited if adequate drug levels are achieved in target sites, whereas excessive drug concentrations linked to ...
Rajoli, Rajith K. R. +3 more
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MEGen: A Physiologically Based Pharmacokinetic Model Generator
Frontiers in Pharmacology, 2011 Physiologically based pharmacokinetic models are being used in an increasing number of different areas. These not only include the human safety assessment of pharmaceuticals, pesticides, biocides and environmental chemicals but also for food animal, wild
George D Loizou, Alex eHogg
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Human physiologically based pharmacokinetic model for propofol
BMC Anesthesiology, 2005 Background Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility.
Schnider Thomas W, Levitt David G
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