Results 151 to 160 of about 2,517,871 (188)
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The quantitation of plasma phytanic acid by mass fragmentography
Clinica Chimica Acta, 1976Plasma phytanic acid has been quantitated by mass fragmentography after its successive reduction and derivatization to the corresponding t-butyldimethylsilyl ether. The latter was estimated by selective ion monitoring of its characteristic (M-57) ion (M/z 355).
G, Phillipou, A, Poulos
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Occurrence of Phytanic Acid in Rumen Bacteria
Nature, 1966THE branched-chain fatty acid 3,7,11,15-tetramethyl-hexadecanoic acid (phytanic acid) has been isolated and identified in butterfat1–4, sheep fat5, ox fat6, ox serum7,8, crude petroleum9 and also in the tissues, serum and urine of humans afflicted with the rare disease referred to as Refsum's syndrome10–12 (heredopathia atactica polyneuritiformis ...
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Phytanic and Pristanic Acid Are Naturally Occuring Ligands
2003Phytanic acid (3,7,11,15 tetramethylhexadecanoic acid) is an isoprenoid-derived 3-methyl fatty acid, which is solely derived from external sources. This branched-chain fatty acid originates from the phytol side chain of chlorophyll. Microorganisms, which are present in the rumen of ruminants, are thought to release phytol from chlorophyll, after which ...
Zomer, Anna W. M. +2 more
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Phytanic acid in tissue lipids in Refsum's disease
Clinica Chimica Acta, 1969Abstract Phytanic acid levels in a variety of tissues and in cerebrospinal fluid in Refsum's disease have been determined. Fatty acid profiles of cholesterol ester, lecithin and triglycerides in the liver, kidney and heart were estimated. Considerable accumulation of phytanic acid in the heart was found, together with raised levels of cholesterol in ...
T R, Skrbic, J N, Cumings
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1972
Phytanic acid storage disease (Refsum’s disease) has presumably been included in the present Symposium under the rubric “...and Allied Disorders.” In that it is an inherited lipidosis and, like so many of them, affects the nervous system, it is to that extent “allied”. However, the differences are several and important.
Daniel Steinberg, David Hutton
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Phytanic acid storage disease (Refsum’s disease) has presumably been included in the present Symposium under the rubric “...and Allied Disorders.” In that it is an inherited lipidosis and, like so many of them, affects the nervous system, it is to that extent “allied”. However, the differences are several and important.
Daniel Steinberg, David Hutton
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Phytanic acid l-menthyl esters
Journal of Chromatography A, 1969Abstract l -Menthyl esters of a naturally occurring (marine) phytanic acid, of an all-synthetic phytanic acid, and of a phytanic acid known to be of 3 d , 7 d , 11 d configuration were compared by GLC. As in the pristanates, the ldd and ddd diastereoisomers were the farthest apart, but in the marine phytanate only two diastereoisomers ...
R.G. Ackman +5 more
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Hepatic α-Oxidation of Phytanic Acid
2002Synthetic 3-methyl-branched chain fatty acids were used to decipher the breakdown of phytanic acid. Based on results obtained in intact or permeabilized rat hepatocytes, rat liver homogenates or subcellular fractions, a revised alpha-oxidation pathway is proposed which appears to be functioning in man as well.
P P, Van Veldhoven +3 more
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NeuroMolecular Medicine, 2018
Docosahexaenoic acid (DHA, 22:6 n-3) is an essential omega-3 (ω-3) long chain polyunsaturated fatty acid of neuronal membranes involved in normal growth, development, and function. DHA has been proposed to reduce deleterious effects in neurodegenerative processes. Even though, some inconsistencies in findings from clinical and pre-clinical studies with
María Belén, Ruiz-Roso +8 more
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Docosahexaenoic acid (DHA, 22:6 n-3) is an essential omega-3 (ω-3) long chain polyunsaturated fatty acid of neuronal membranes involved in normal growth, development, and function. DHA has been proposed to reduce deleterious effects in neurodegenerative processes. Even though, some inconsistencies in findings from clinical and pre-clinical studies with
María Belén, Ruiz-Roso +8 more
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The formation of alpha-hydroxy phytanic acid from phytanic acid in mammalian tissues
Biochemical and Biophysical Research Communications, 1967S C, Tsai +4 more
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ACCUMULATIONS OF PHYTANIC ACID IN REFSUM'S DISEASE
The Lancet, 1969R A, Kark, J P, Blass, L, Baker
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