Results 51 to 60 of about 4,018 (220)

Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]

open access: yes, 2008
Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges   +4 more
core   +2 more sources

Phytanic acid alpha-oxidation: accumulation of 2-hydroxyphytanic acid and absence of 2-oxophytanic acid in plasma from patients with peroxisomal disorders.

open access: yesJournal of Lipid Research, 1992
A stable isotope dilution method was developed for the measurement of 2-hydroxyphytanic acid and 2-oxophytanic acid in plasma. In plasma from healthy individuals and from patients with Refsum's disease, 2-hydroxyphytanic acid was found at levels less ...
HJ ten Brink   +5 more
doaj   +1 more source

Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao   +6 more
wiley   +1 more source

Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy [PDF]

open access: yes, 2018
Consumption of diets containing medium-chain TAG (MCT) has been shown to confer neuroprotective effects. We aim to identify the global metabolic perturbations associated with consumption of a ketogenic diet (medium-chain TAG diet (MCTD)) in dogs with ...
Benjamini   +10 more
core   +2 more sources

Improved electroretinographic responses following dietary intervention in a patient with Refsum disease

open access: yesJIMD Reports, 2020
Refsum disease is a rare inherited metabolic disorder arising from a defect in peroxisomal metabolism. Patients lack the functional enzyme phytanoyl‐CoA hydroxylase, resulting in perturbed alpha oxidation of fatty acids.
Matthew D. Benson   +3 more
doaj   +1 more source

Phytanic Acid is a Retinoid X Receptor Ligand [PDF]

open access: yesEuropean Journal of Biochemistry, 1996
Metabolic defects in phytanic acid catabolism have been shown to be connected with a number of human diseases which can lead to lethal defects of the nervous system and other organs. These effects are probably a result of the very high accumulation of phytanic acid in tissues throughout the body, due to defects in phytanic acid oxidation, the ...
P K, Lemotte, S, Keidel, C M, Apfel
openaire   +2 more sources

Cultured Meat: A Multidimensional Review of Technological, Nutritional, Ethical, and Regulatory Advances (2020–2025)

open access: yesJournal of Food Science, Volume 91, Issue 2, February 2026.
ABSTRACT Global food systems face increasing environmental, ethical, and health‐related challenges, prompting the search for sustainable protein alternatives. Cultured meat has emerged as a promising option, offering potential benefits such as reduced environmental impact, improved animal welfare, and nutritional customization.
Ana Carolina Agne Ferreira Zão   +3 more
wiley   +1 more source

Sterol carrier protein-2/sterol carrier protein-x expression differentially alters fatty acid metabolism in L cell fibroblasts

open access: yesJournal of Lipid Research, 2003
Sterol carrier protein-2 (SCP-2) and SCP-x are ubiquitous proteins found in all mammalian tissues. Although both proteins interact with fatty acids, their relative contributions to the uptake, oxidation, and esterification of straight-chain (palmitic ...
Barbara P. Atshaves   +2 more
doaj   +1 more source

Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

open access: yesScientific Reports, 2022
Peroxisomes play an important role in the metabolism of a variety of biomolecules, including lipids and bile acids. Peroxisomal Membrane Protein 4 (PXMP4) is a ubiquitously expressed peroxisomal membrane protein that is transcriptionally regulated by ...
Maaike Blankestijn   +13 more
doaj   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

open access: yesGlia, Volume 73, Issue 12, Page 2338-2352, December 2025.
Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis   +2 more
wiley   +1 more source

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