Results 71 to 80 of about 4,018 (220)

Compartmentalization of the Edinburgh Human Metabolic Network [PDF]

, 2010
Background Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in different organelles may lead to distinct functions of the same protein and ...
Tong Hao, Hong-Wu Ma, Xue-Ming Zhao, Igor Goryanin   +3 more
core   +3 more sources

Phytanoyl‐CoA hydroxylase activity is induced by phytanic acid [PDF]

European Journal of Biochemistry, 2000
Phytanic acid (3,7,11,15‐tetramethylhexadecanoic acid) is a branched‐chain fatty acid present in various dietary products such as milk, cheese and fish. In patients with Refsum disease, accumulation of phytanic acid occurs due to a deficiency of phytanoyl‐CoA hydroxylase, a peroxisomal enzyme containing a peroxisomal targeting signal 2.
Zomer, A. W., Jansen, G. A., van der Burg, B., Verhoeven, N. M., Jakobs, C., van der Saag, P. T., Wanders, R. J., Poll-The, B. T.   +7 more
openaire   +3 more sources

Treatment of Inborn Errors by Product Replacement: The Example of Inborn Errors of Bile Acid Synthesis

Journal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.
ABSTRACT Many inborn errors of metabolism affect pathways involved in the synthesis of a metabolite that has an important biochemical or physiological function, and adverse effects of the disorder can be attributed to the lack of this metabolite. Thus, there is the opportunity for treatment by ‘product replacement’. One of the disorders in the pathways
Peter T. Clayton, Rohit Hirachan, Elaine Murphy   +2 more
wiley   +1 more source

Dietary factors and risk for advanced prostate cancer [PDF]

, 2014
Prostate cancer is the second most common cancer among men worldwide. Although some nutrients have been linked to the development of total prostate cancer, it remains unclear whether these nutrients modulate the risk of its clinically significant form ...
Gathirua-Mwangi, Wambui G., Zhang, Jianjun   +1 more
core   +1 more source

Biomedical Activities of Florasol

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
Florasol is an acyclic alcohol of diterpene regularly available in certain aromatic plants' essential oils, such as Lantana radula and Cleome serrata. Florasol is a plant phytochemical phytoconstituent which is extensively spread in nature. Florasol is a
Paramasivam Selvakumar
doaj   +1 more source

Potential Applications of Zingiber officinale, Clitoria ternatea, and Coccinia grandis for Enhancing the Functionality of Set Yogurts

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
In this study, aqueous extracts of ginger, blue butterfly pea flower, and ivy leaf were fortified to the yogurts and evaluated the sensorial, physicochemical, and functional characteristics of yogurt along with the protein interactions. Results revealed that the fortification of all the plant extracts had a significant impact on the sensorial ...
Yohan Jayaweera, Mayumi Silva, Jayani Chandrapala, Rumesh Liyanage, K. G. L. R. Jayathunge, Amali U. Alahakoon   +5 more
wiley   +1 more source

A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways

Journal of Lipid Research, 2005
Branched-chain fatty acids (such as phytanic and pristanic acid) are ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor α (PPARα) in vitro.
J. Gloerich, N. van Vlies, G.A. Jansen, S. Denis, J.P.N. Ruiter, M.A. van Werkhoven, M. Duran, F.M. Vaz, R.J.A. Wanders, S. Ferdinandusse   +9 more
doaj   +1 more source

A study on the causes for the elevated n−3 fatty acids in cows' milk of alpine origin [PDF]

, 2018
The influence of grass-only diets either from rye-grass-dominated lowland pastures (400 m above sea level) or botanically diverse alpine pastures (2000 m) on the FA profile of milk was investigated using three groups of six Brown Swiss cows each.
Kreuzer, Michael, Leiber, Florian, Leo Scheeder, Martin, Nigg, Daniel, Wettstein, Hans-Rudolf   +4 more
core  

Safety assessment of the mixture of methyl-branched and linear C14–C18 alkanamides, derived from fatty acids, for use in food contact materials [PDF]

, 2017
Publisher ...
Barthélemy, Eric, Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kolf-Clauw, Martine, Kärenlampi, Sirpa, Lampi, Eugenia, Mennes, Wim, Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Svensson, Kettil, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs

Journal of Lipid Research, 2004
Geranylgeranoic acid (GGA; all-trans 3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenoic acid) has been shown to induce apoptosis in a human hepatoma-derived cell line, HuH-7.
Yoshihiro Shidoji, Hiroko Ogawa
doaj   +1 more source