Results 81 to 90 of about 901,118 (265)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Monaldi Archives for Chest Disease, 2016 Background. AAT deficiency is not a rare disease, but one of the most common congenital disorders increasing susceptibility of individuals with this deficiency to both lung and liver disease as well as other several adverse health effects.
F.J. de Serres +2 more
doaj +1 more source
Свойство $K(\pi,1)$ для неособых отмеченных кривых над конечными полями
Известия Российской академии наук. Серия математическая, 2015 В случае неособых отмеченных кривых $(X,T)$ над конечными полями характеристики $p$ изучается свойство $K(\pi,1)$ для простого $p$. Доказано, что $(X,T)$ обладает свойством $K(\pi,1),$ если $X$ - аффинная кривая. Если $X$ - собственная кривая, приведены примеры, показывающие, что свойство может быть как выполнено, так и не выполнено.
Philippe Lebacque, Alexander Schmidt
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
P1260: UNRAVELING THE GENETICS OF TRANSFORMED SPLENIC MARGINAL ZONE LYMPHOMA
HemaSphere, 2022 M. Grau +25 more
doaj +1 more source
Monaldi Archives for Chest Disease, 2016 Background. AAT deficiency is not a rare disease, but one of the most common congenital disorders increasing susceptibility of deficiency individuals to both lung and liver disease as well as other several adverse health effects.
F.J. de Serres +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Not all free arrangements are $K(\pi,1)$
, 1994 Comment: 5 ...
Edelman, Paul H., Reiner, Victor
openaire +2 more sources