Results 91 to 100 of about 862,963 (270)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

BREEDING OF RICE VARIETIES WITH PYRAMIDING GENES TOLERANT TO DISEASES

Зерновое хозяйство России, 2018
Rice can significantly decrease the harvest of grain when it’s damaged with a dangerous fungus ‘Pyricularia grisea’ (rice blast). Single genes resistant to the pathogen are usually unefficient. That’s why it’s necessary to breed productive rice varieties,
P. I. Kostylev, E. V. Krasnova, A. A. Redkin, Zh. M. Mukhina, E. V. Dubina   +4 more
doaj   +2 more sources

Marker assisted rice breeding for resistance to biotic and abiotic stressors

BIO Web of Conferences, 2020
Due to the fact that blast (causative agent – Pyricularia oryzae Cav.) is considered to be one of the harmful diseases of rice around the world, weeds compete with the crop for light, mineral nutrition and space, the accelerated development of resistant ...
Dubina Elena, Kostylev Pavel, Garkusha Sergey, Ruban Margarita, Pischenko Dmitry   +4 more
doaj   +1 more source

Going against the flow: A critical analysis of virtual water trade in the context of India's National River Linking Programme [PDF]

, 2007
Virtual water trade has been promoted as a tool to address national and regional water scarcity. In the context of international (food) trade, this concept has been applied with a view to optimize the flow of commodities considering the water endowments ...
Hoekstra, Arjen Y., Kampman, Doeke A., Verma, Shilp, Zaag, Pieter van der   +3 more
core   +1 more source

Aliskiren, enalapril, or aliskiren and enalapril in heart failure [PDF]

, 2016
BACKGROUND Among patients with chronic heart failure, angiotensin-converting–enzyme (ACE) inhibitors reduce mortality and hospitalization, but the role of a renin inhibitor in such patients is unknown.
], Akshay S. Desai, Barry M. Massie, Claudio Borghi, for the ATMOSPHERE Committees Investigators [, Georgia Tarnesby, Henry Krum, John J.V. McMurray, Kenneth Dickstein, Lars V. Køber, M. Atif Ali, Nicola Greenlaw, Qing Shao, Scott D. Solomon, William T. Abraham, Yanntong Chiang   +15 more
core   +5 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Predicting suicides after outpatient mental health visits in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). [PDF]

, 2017
The 2013 US Veterans Administration/Department of Defense Clinical Practice Guidelines (VA/DoD CPG) require comprehensive suicide risk assessments for VA/DoD patients with mental disorders but provide minimal guidance on how to carry out these ...
Army STARRS Collaborators, Bliese, P, Bossarte, RM, Bromet, EJ, Fullerton, CS, Gilman, SE, Ivany, C, Kessler, RC, Lewandowski-Romps, L, Millikan Bell, A, Naifeh, JA, Nock, MK, Petukhova, MV, Reis, BY, Rosellini, AJ, Sampson, NA, Stein, MB, Ursano, RJ, Zaslavsky, AM   +18 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Improving panicle blast resistance and fragrance in a high-quality japonica rice variety through breeding

Frontiers in Plant Science
IntroductionHuruan1212 (HR1212) is well-regarded for its superior eating and cooking quality in the lower reaches of the Yangtze River in China. Still, its high susceptibility to rice panicle blast and lack of fragrance have limited its further spread ...
Junhua Ye, Junhua Ye, Kai Wang, Yi Wang, Zhipeng Zhao, Ying Yan, Hang Yang, Lixia Zhang, Lixia Zhang, Zejun Hu, Zejun Hu, Zhenying Shi, Dapeng Sun, Jianjiang Bai, Liming Cao, Liming Cao, Shujun Wu, Shujun Wu   +17 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source