Results 171 to 180 of about 59,033 (267)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Intracoronary adjunctive therapies for ST-elevation myocardial infarction: a network meta-analysis of trials. [PDF]

Eur Heart J Cardiovasc Pharmacother
Laborante R, Bianchini E, Ciliberti G, Paglianiti DA, Filomia S, Bianchini F, Galli M, Biondi-Zoccai G, Serruys PW, Crea F, Patti G, Savarese G, Trani C, Burzotta F, D'Amario D.   +14 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Association Between Calcaneal Inclination Angle and Spinal and Lower Limb Alignment: A Retrospective Radiographic Analysis. [PDF]

Diagnostics (Basel)
Han Y, Jeon S, Woo H, Ha W, Park TY, Lee JH, Lee J.   +6 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Unlocking carrier confluence in covalent organic frameworks for efficient photoreduction of dilute nitrate to ammonia. [PDF]

Nat Commun
Su Y, Wang Z, Deng X, Yin SF, Chen P.
europepmc   +1 more source

Capital constraints and net present value optimization in project scheduling [PDF]

, 2016
Leyman, Pieter, Vanhoucke, Mario
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Hydrated metal charge density as a universal descriptor explaining mechanistic variations in periodate activation toward pollutant degradation. [PDF]

Nat Commun
Qian Y, Sun Y, Xu J, Gao P, Xue G, Zhou X, Zhang Y, Chen J.   +7 more
europepmc   +1 more source

Dundee Discussion Papers in Economics 103:The illusions, reality and implications of British government expenditure 1948- 1968 [PDF]

, 1999
Morelli, Carlo J.
core