Results 281 to 290 of about 626,720 (343)

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Phellodendron amurense Rupr. Polysaccharides protects against diabetic nephropathy via alteration of PI3K/GSK-3β/Nrf2/TGF-β/Smad signaling pathway and gut microbiota. [PDF]

Nat Prod Bioprospect
Mei M, Sun H, Zhang K, Zhang F, Sun S, Zhang Y.   +5 more
europepmc   +1 more source

γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway. [PDF]

Front Pharmacol
Wei J, Xie J, He Z, Feng X.
europepmc   +1 more source

Hesperetin alleviates sepsis-associated acute respiratory distress syndrome via the PI3K/Akt/PTEN axis. [PDF]

Sci Rep
Ruan H, Yang D, Wang N, Liu J, Huang L.
europepmc   +1 more source

Autophagy targeted nano-medicine in norphytane atrophic arthritis model: Beclin1/XBP/PTEN/STAT-3A genetic profile. [PDF]

Future Sci OA
O Kadry M, Abdel-Megeed RM.
europepmc   +1 more source