Results 131 to 140 of about 62,994 (190)

Bulk gauge and matter fields in nested warping: I. the formalism

, 2015
The lack of evidence for a TeV-mass graviton has been construed as constricting the Randall-Sundrum model. However, a doubly-warped generalization naturally avoids such restrictions.
Arun, Mathew Thomas, Choudhury, Debajyoti   +1 more
core   +1 more source

Ustilago maydis Phosphatidic Acid and Phosphatidylserine‐Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy, Rituparna Mondal, Anupama Ghosh   +2 more
wiley   +1 more source

Visually Transparent and Scalable Cu(In,Ga)Se2 Solar Cells Through Spatial Segmentation

Solar RRL, Volume 10, Issue 8, 27 April 2026.
Spatially‐segmented Cu(In,Ga)Se2 thin films can be implemented as colour‐neutral photovoltaic windows. This segmentation approach preserves material quality and colour integrity by defining indiscernible micro‐stripes rather than thinning the absorber.
Nuno Rodrigues, José Fonseca, Pedro Santos, Rico Gutzler, Wolfram Witte, Shilpi Shital, Phillip J. Dale, Pedro Anacleto, Sascha Sadewasser   +8 more
wiley   +1 more source

Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability. [PDF]

, 2019
There is increasing evidence that the lysosome is involved in the pathogenesis of a variety of neurodegenerative disorders. Thus, mechanisms that link lysosome dysfunction to the disruption of neuronal homeostasis offer opportunities to understand the ...
Dickson, Eamonn J, Dixon, Rose E, Ory, Daniel S, Tiscione, Scott A, Vivas, Oscar   +4 more
core   +2 more sources

The irreversible thermodynamics of curved lipid membranes

, 2017
The theory of irreversible thermodynamics for arbitrarily curved lipid membranes is presented here. The coupling between elastic bending and irreversible processes such as intra-membrane lipid flow, intra-membrane phase transitions, and protein binding ...
Mandadapu, Kranthi K., Sahu, Amaresh, Sauer, Roger A.   +2 more
core   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Current understanding of ENaC regulation by P2Y2/PLC/PI(4,5)P2 pathway

Purinergic Signalling
The epithelial sodium channel (ENaC) localized in the cell membrane is crucial for sodium transport and blood pressure regulation. Discovered in frog skin, ENaC is expressed in the colon, lungs, exocrine glands, and most notably in the distal nephron of the kidneys, where it limits sodium reabsorption.
Abd El-Aziz, Tarek Mohamed, Al-Sabi, Ahmed, Seale, Lucia A., Soares, Antonio G.   +3 more
openaire   +2 more sources

PIP5Kγ Mediates PI(4,5)P2/Merlin/LATS1 Signaling Activation and Interplays with Hsc70 in Hippo-YAP Pathway Regulation. [PDF]

Int J Mol Sci, 2023
Le DDT, Le TPH, Lee SY.
europepmc   +1 more source

LPLAT11/MBOAT7-driven phosphatidylinositol remodeling ensures radial glial cell integrity in developing neocortex

iScience
Summary: Phosphatidylinositol (PI) is highly enriched in arachidonic acid, an essential polyunsaturated fatty acid for brain development. This enrichment is mediated by the phospholipid remodeling enzyme lysophospholipid acyltransferase 11 (LPLAT11 ...
Yuki Ishino, Yusuke Kishi, Taiga Iwama, Naohiro Kuwayama, Hiroyuki Arai, Yukiko Gotoh, Junken Aoki, Nozomu Kono   +7 more
doaj   +1 more source

Cholesterol promotes clustering of PI(4,5)P2 driving unconventional secretion of FGF2. [PDF]

J Cell Biol, 2022
Lolicato F, Saleppico R, Griffo A, Meyer A, Scollo F, Pokrandt B, Müller HM, Ewers H, Hähl H, Fleury JB, Seemann R, Hof M, Brügger B, Jacobs K, Vattulainen I, Nickel W.   +15 more
europepmc   +1 more source