Stilbenes in Red Wine: Formation and Biological Potential of Resveratrol and Piceid Dimers [PDF]
Resveratrol and its glucoside, piceid, are the primary stilbenes present in wine. These compounds are well known for their pharmaceutical properties. However, these compounds can undergo chemical transformations in wines, such as polymerization in the ...
Ayoub Jaa +7 more
doaj +9 more sources
Characterization of Grape Cane Stilbenoids and Their Photo-Degradation Products by HPLC-DAD Coupled With Trapped Ion Mobility Spectrometry and High-Resolution Tandem Mass Spectrometry. [PDF]
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Besrukow P +3 more
europepmc +2 more sources
Novel Bioactive Multifunctional Polyphenols: A Chemo-Enzymatic Approach. [PDF]
One‐step synthesis of complex alkyl oxystilbenin glucosides (6‐47% yield) in alcoholic medium. Switching to ter‐BuOH as solvent afforded δ‐Viniferin diglucoside, with high selectivity and high yield (> 90%), that can be upgraded by enzymatic esterification to alkyl δ‐Viniferin diglucosides.
Flourat AL +8 more
europepmc +2 more sources
Biological Activity of Stilbenoids Against Fungal, Parasitic, and Viral Pathogens [PDF]
Stilbenoids are plant-derived chemical compounds that are classified as phytoalexins; recent focus has been drawn, especially on astringin, piceid, piceatannol, pterostilbene, pinosylvin, and resveratrol.
Aristodemos-Theodoros Periferakis +9 more
doaj +2 more sources
Use of Germination to Enhance Resveratrol Content and Its Anti-Inflammatory Activity in Lipopolysaccharide-Stimulated RAW264.7 Cells [PDF]
Inflammation is triggered by a variety of danger signals and is now a worldwide concern. Resveratrol, a natural nonflavonoid polyphenol found in naturally consumed plants and foods, has a wide spectrum of bioactive potency.
Chaiwat Monmai +2 more
doaj +2 more sources
Chromatographic Analysis and Enzyme Inhibition Potential of Reynoutria japonica Houtt.: Computational Docking, ADME, Pharmacokinetic, and Toxicokinetic Analyses of the Major Compounds [PDF]
Background: Reynoutria japonica Houtt. has been used for inflammatory diseases, skin burns, and high cholesterol in traditional Chinese medicine, and the roots and rhizomes of the plant were registered in the Chinese Pharmacopoeia.
Tugsen Buyukyildirim +6 more
doaj +2 more sources
Resveratrol Content Profiles and Their Correlation with Multidimensional Quality in Different Peanut Cultivars [PDF]
Resveratrol is a promising polyphenolic bioactive compound found in peanuts. However, the distribution of cis- and trans-resveratrol and their glycosides varies significantly among cultivars, and their correlations with other quality traits remain ...
Yumeng Hu +6 more
doaj +2 more sources
Exploring cotton plant compounds for novel treatments against brain-eating Naegleria fowleri: An In-silico approach. [PDF]
To find potential inhibitors of Naegleria fowleri S-adenosyl-L-homocysteine hydrolase (NfSAHH), a brain-eating parasite, structure-based drug design was adopted. N. fowlerica causes primary amebic meningoencephalitis (PAM), a fatal central nervous system
Aqal Zaman +11 more
doaj +2 more sources
The Effect of External Treatment of Arabidopsis thaliana with Plant-Derived Stilbene Compounds on Plant Resistance to Abiotic Stresses [PDF]
Stilbenes are a group of plant phenolic secondary metabolites, with trans-resveratrol (3,5,4′-trihydroxy-trans-stilbene) being recognized as the most prominent and studied member.
Olga A. Aleynova +7 more
doaj +2 more sources
UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking [PDF]
Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limitations. However,
Shijiao Zhang +5 more
doaj +2 more sources

