Results 101 to 110 of about 981 (132)

Thermal inactivation of pichinde virus

Journal of Virological Methods, 1985
Detailed information regarding the kinetics of thermal inactivation of Pichinde, an arenavirus, is presented. Inactivation of virus infectivity proceeded as a first order reaction over the temperature range 22-53 degrees C. The determined inactivation rates analysed as a function of absolute temperature revealed that two different reactions were ...
C R Howard
exaly   +3 more sources

Ribonucleoprotein complexes associated with virions of Pichinde virus and Pichinde virus-infected cells

Medical Microbiology and Immunology, 1986
Paul Young, C R Howard
exaly   +5 more sources

Neurochemical changes in brains of mice infected with Pichinde virus

Medical Microbiology and Immunology, 1986
A D T Barrett, A D Barrett, Cross A J
exaly   +3 more sources

Regulation of Pichinde virus replication in Vero and BHK-21 cells

Medical Microbiology and Immunology, 1986
Paul Young, C R Howard
exaly   +3 more sources

Strandedness of Pichinde virus RNA

Journal of Virology, 1977
The Pichinde virus RNA did not possess the following characteristics of eucaryotic mRNA: polyadenylic acid sequence, capped methylated structure, and ability to direct protein synthesis in vitro. Polysomal RNA extracted from cells infected with Pichinde virus reannealed with 32P-labeled virus RNA, protecting about 60% of the latter against RNase ...
W C, Leung, H P, Ghosh, W E, Rawls
openaire   +2 more sources

The nucleoprotein of Pichinde virus expressed by a vaccinia-Pichinde virus recombinant partially protects hamsters from lethal virus challenge

Archives of Virology, 1994
Syrian hamsters, strain MHA/Lak, are susceptible to intraperitoneal infection with Pichinde virus and die from an overwhelming viremia. We have studied the ability of a vaccinia-Pichinde recombinant virus expressing amino acids 51-561 of the viral nucleoprotein (VVNP51-561) to protect from lethal Pichinde virus infection.
D Y, Ozols, W E, Rawls, K L, Rosenthal, D G, Harnish   +3 more
openaire   +2 more sources

Characterization of temperature-sensitive mutants of Pichinde virus

Journal of Virology, 1988
The synthesis of viral proteins and S RNAs in cells infected with 12 temperature-sensitive (ts) mutants of Pichinde virus was characterized. The mutants could be divided into five groups on the basis of the patterns of radiolabeled proteins immunoprecipitated from infected-cell lysates.
M, Shivaprakash, D, Harnish, W, Rawls
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Characterization of Pichinde virus infection of cells of the monocytic lineage

Journal of Virology, 1991
To establish a model of viral infection of monocytes, we examined infection of human cells and cell lines of the monocytic series with the arenavirus Pichinde virus. We demonstrate for the first time that human peripheral blood monocytes are susceptible to Pichinde virus infection, as shown by immunoprecipatation of virus-specific polypeptides from ...
S J, Polyak, W E, Rawls, D G, Harnish
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Virion-associated ribosomes are not required for the replication of Pichinde virus

Virology, 1977
Abstract Ribosomes of host cell origin have been isolated from Pichinde virus. A cell mutant with a temperature-sensitive defect in protein synthesis and 60 S ribosomal subunits was employed to study the role of virion-associated ribosomes in the replication of Pichinde virus. Virions carrying the temperature-sensitive ribosomes replicated as well at
W C, Leung, W E, Rawls
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Biophysical and Biochemical Studies of Pichinde Virus

1973
Pichinde virus, a member of the arenavirus group, was found to contain single-stranded RNA. The RNA consisted of 5 discernible components corresponding to 31S, 28S, 22S, 18S and 4 to 6S. The 28S and 18S RNA’s appeared to be of host cell origin and the 4 to 6S RNA was probably from the same source.
W. E. Rawls, Blanca A. Ramos, M. F. Carter   +2 more
openaire   +1 more source