M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. [PDF]
PLoS ONE, 2012 Indoleamine 2,3-dioxygenesae-1 (IDO-1) catalyses the initial, rate-limiting step in tryptophan metabolism, thereby regulating tryptophan availability and the formation of downstream metabolites, including picolinic and quinolinic acid.
Antje Blumenthal +8 more
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Applied Sciences, 2022 Topography of tungsten should be assured at a minimum through chemical mechanical planarization (CMP) in the metal gate structures (e.g., buried gates, replacement metal gates) and via contact in the middle of line (MOL) process for sub−7 nm ...
Kangchun Lee, Jihoon Seo
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Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac. [PDF]
EJNMMI Radiopharm Chem, 2019 BackgroundActinium-225 (225Ac, t1/2 = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and 225Ac ...
Ramogida CF +14 more
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Identification and Characterization of a Novel pic Gene Cluster Responsible for Picolinic Acid Degradation in Alcaligenes faecalis JQ135. [PDF]
J Bacteriol, 2019 Picolinic acid is a common metabolite of l-tryptophan and some aromatic compounds and is an important intermediate in organic chemical synthesis. Although the microbial degradation/detoxification of picolinic acid has been studied for over 50 years, the ...
Qiu J +8 more
europepmc +2 more sources
Iridium Corroles Exhibit Weak Near-Infrared Phosphorescence but Efficiently Sensitize Singlet Oxygen Formation. [PDF]
, 2020 Six-coordinate iridium(III) triarylcorrole derivatives, Ir[TpXPC)]L2, where TpXPC = tris(para-X-phenyl)corrole (X = CF3, H, Me, and OCH3) and L = pyridine (py), trimethylamine (tma), isoquinoline (isoq), 4-dimethylaminopyridine (dmap), and 4-picolinic ...
Borisov, Sergey M +3 more
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RELAXATION OF ISOLATED AORTA OF THE RABBIT BY PICOLINIC ACIDS [PDF]
British Journal of Pharmacology, 1977 When the isolated thoracic aorta of the rabbit was contracted with prostaglandin F2α, 5‐alkylpicolinic acids produced dose‐dependent relaxations. Picolinic acid, 2,5‐pyridinedicarboxylic acid and 5‐acetylpicolinic acid which do not have the 5‐alkyl residue failed to relax blood vessels.
H. Hidaka, M. Asano
openaire +3 more sources
European Psychiatry, 2021 Introduction The tryptophan pathway along with its two branches of metabolism to serotonin and kynurenine seems to be affected in major depression.
R. Colle +4 more
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Solution Equilibrium Studies of Anticancer Ruthenium(II)-η6-p-cymene Complexes of Pyridinecarboxylic Acids [PDF]
, 2014 Stoichiometry and stability of antitumor ruthenium(II)-η6-p-cymene complexes of picolinic acid and its 6-methyl and 6-carboxylic acid derivatives were determined by pH-potentiometry, 1H NMR spectroscopy and UV–Vis spectrophotometry in aqueous solution in
Alessio +56 more
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Acta Scientiarum: Biological Sciences, 2011 The effect of 2-pyridinecarboxylic acid (picolinic acid) on trypanosomes of the subgenus Schizotrypanum isolated from the bat Phyllostomus hastatus was determined in this study. Picolinic acid, at 50 µg mL-1, inhibited epimastigote growth by 99% after 12
Paulo Roberto Ceridório Corrêa +5 more
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Rhodium and copper 6-methylpicolinate complexes. Structural diversity and supramolecular interaction study [PDF]
, 2016 Seven new coordination compounds with 6-methylpicolinic acid (6-HMepic) and rhodium(III) or copper(II) of formula [Rh(6-Mepic)3] (1), [Rh(6-Mepic)2(H2O)Cl] (2), [Rh(6-HMepic)(6-Mepic)Cl2]·3.5(H2O) (3), [Cu(6-Mepic)2(H2O)]·H2O (4), [Cu(6-Mepic)2]n, (5 ...
Amo-Ochoa, P. +3 more
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