Synthesis of ethyl 4-(2-fluoro-4-nitrophenoxy) picolinate [PDF]
Cancer has seriously affected people's production and life. The appearance of anti-cancer drugs has brought good news to people. Ethyl 4-(2-fluoro-4-nitrophenoxy) picolinate is an important basic skeleton of a small molecule inhibitor of c-Met and a ...
Dai Jintian +6 more
doaj +1 more source
DFT-Assisted Design and Evaluation of Bifunctional Amine/Pyridine-Oxazoline Metal Catalysts for Additions of Ketones to Unactivated Alkenes and Alkynes [PDF]
Bifunctional catalyst systems for the direct addition of ketones to unactivated alkenes/alkynes were designed and modeled by density functional theory (DFT).
Dockendorff, Chris +2 more
core +3 more sources
Association Between the Dutch Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND-NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study. [PDF]
Following the MIND diet may support brain health in older adults at risk of cognitive decline by influencing tryptophan (TRP) metabolism. Plasma samples and dietary intake data from the HELI intervention trial were used. Bivariate latent change score modeling analysis showed that greater adherence to the MIND diet was linked to higher tryptophan levels,
Beers S +10 more
europepmc +2 more sources
Use of superheated liquids for the extraction of non-volatile compounds from wood: HPLC studies [PDF]
A study of the extraction of oak wood compounds using superheated water-ethanol mixtures ranging from 10 to 60% ethanol is reported. Identification and characterization of the extracted compounds have been made by high performance liquid chromatography ...
Chatonnet +12 more
core +1 more source
Non-conventional trans-platinum complexes functionalized with RDG peptides: chemical and cytototoxicity studies [PDF]
In order to target platinum complexes to cancer cells, trans-Pt(II) or trans-Pt(IV) complexes were bioconjugated to the cyclic peptide cRGDfK (cRGD), with affinity for αvβ3 integrin receptors, through their 4-picolinic acid spectator ligands.
Abramkin +21 more
core +2 more sources
Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen [PDF]
Dipicolinic acid (DPA) is a distinctive biomarker for bacterial spores. Here, we present the successful demonstration of dramatic Switch-OFF sensing of DPA using an easily synthesised Eu(III) phosphor applied primarily in light-emitting devices.
Aspinall +18 more
core +1 more source
Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review
BackgroundMultiple sclerosis (MS) is a debilitating neurodegenerative disorder characterized by axonal damage, demyelination, and perivascular inflammatory lesions in the white matter of the central nervous system (CNS). Kynurenine pathway (KP), which is
Mobina Fathi +10 more
doaj +1 more source
Synthesis of highly functionalized 2,2'-bipyridines by cyclocondensation of β-ketoenamides – scope and limitations [PDF]
The scope of a flexible route to unsymmetrically functionalized bipyridines is described. Starting from 1,3-diketones 1a–e, the corresponding β-ketoenamines 2a–e were converted into different β-ketoenamides 3a–g by N-acylation with 2-pyridinecarboxylic ...
Hommes, Paul, Reissig, Hans-Ulrich
core +2 more sources
Catalytic and mechanistic studies into the epoxidation of styrenes using manganese complexes of structurally similar polyamine ligands [PDF]
The synthesis and catalytic activity of manganese(ii) complexes of two polyamine ligands is reported which highlights how a small structural change in the ligand affects the overall catalytic behaviour.
Al-Safadi, R +5 more
core +1 more source
Sorption of picolinic acid by Cu(II)-containing sulfocationite KU-2-8
Objectives. To study the equilibrium distribution of components between KU-2-8 sulfocationite and an aqueous solution containing picolinic acid and Cu(II); to show the possibility of immobilization of cations of picolinic acid and Cu2+ in sulfonic cation
H. N. Altshuler +3 more
doaj +1 more source

