Results 11 to 20 of about 6,282 (195)

A Simple Method for Synthesis of Active Esters of Isonicotinic and Picolinic Acids

Molecules, 2001
A method for preparation of the p-nitrophenyl-, N-hydroxysuccinimidyl- and pentafluorophenyl esters of isonicotinic and picolinic acids from the corresponding acids is reported.
Jørn B. Christensen
doaj   +3 more sources

Association Between the Dutch Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND-NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study. [PDF]

Mol Nutr Food Res
Following the MIND diet may support brain health in older adults at risk of cognitive decline by influencing tryptophan (TRP) metabolism. Plasma samples and dietary intake data from the HELI intervention trial were used. Bivariate latent change score modeling analysis showed that greater adherence to the MIND diet was linked to higher tryptophan levels,
Beers S, de Groot LCPGM, van Loenen MR, Remie LB, Bromhaar MG, Anesi A, Vrhovsek U, Oosterman JM, Aarts E, van Trijp MPH, Vermeiren Y.   +10 more
europepmc   +2 more sources

Functional changes in the gut microbiota are associated with the intestinal phenotype in A20 haploinsufficiency. [PDF]

Pediatr Allergy Immunol
Abstract Background A20 haploinsufficiency (HA20) is an autoinflammatory disease driven by pathogenic variants in TNFAIP3, which plays a crucial role in regulating immune responses. The clinical manifestations of HA20 resemble those of inflammatory bowel disease (IBD), with prominent gastrointestinal (GI) involvement.
Elhani I, Bredon M, Enea D, Desmons A, Arrive L, Bazille C, Lefevre A, Aouba A, Bigot A, de Moreuil C, Alonso I, Blasco H, Creusot L, Dupuy C, Emond P, Krasniqi P, Lamaziere A, Oeuvray C, Rainteau D, Svrcek M, Rolhion N, Sokol H, Georgin-Lavialle S.   +22 more
europepmc   +2 more sources

The comparative study of linear solvatation energy relationship for the reactivity of pyridine carboxylic acids with diazodiphenylmethane in protic and aprotic solvents [PDF]

Journal of the Serbian Chemical Society, 2012
Protic and aprotic solvent effects on the reactivity of picolinic, nicotinic and isonicotinic acid, as well as of some substituted nicotinic acids with diazodiphenylmethane (DDM) were investigated.
Drmanić Saša Ž., Nikolić Jasmina B., Marinković Aleksandar D., Jovanović Bratislav Ž.   +3 more
doaj   +1 more source

Polymorphism in the 1/1 Pterostilbene/Picolinic Acid Cocrystal [PDF]

Crystal Growth & Design, 2021
The crystal structures of two new polymorphs of the 1/1 pterostilbene/picolinic acid cocrystal have been analyzed by single-crystal X-ray diffraction and studied by means of DFT calculations and a set of computational tools (QTAIM, NCIplot, MEP). The observation of a new R2 2(10) synthon in each of the two polymorphs has been analyzed energetically ...
Rafael Barbas, Mercè Font-Bardia, Antonio Frontera, Rafel Prohens   +3 more
openaire   +2 more sources

What if Cocrystallization Fails for Neutral Molecules? Screening Offered Eutectics as Alternate Pharmaceutical Materials: Leflunomide-a Case Study [PDF]

Pharmaceutical Sciences, 2019
Background: The manuscript is aimed to optimize the biopharmaceutical parameters of a poorly soluble, neutral anti-rheumatic drug ‘leflunomide’ by preparing its non-covalent derivatives (NCDs).
Madhu Bala, Manoj Kumar Gautam, Renu Chadha   +2 more
doaj   +1 more source

Iron-Catalyzed Oxidation of 1-Phenylethanol and Glycerol With Hydrogen Peroxide in Water Medium: Effect of the Nitrogen Ligand on Catalytic Activity and Selectivity

Frontiers in Chemistry, 2020
The iron(II) complexes [Fe(bpy)3](OTf)2 (bpy = 2,2'-bipyridine; OTf = CF3SO3) (1) and [Fe(bpydeg)3](OTf)2 (bpydeg = N4,N4-bis(2-(2-methoxyethoxy)ethyl) [2,2'-bipyridine]-4,4'-dicarboxamide) (2), the latter being a newly synthesized ligand, were employed ...
Dimitri Ros, Teresa Gianferrara, Corrado Crotti, Erica Farnetti   +3 more
doaj   +1 more source

Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy

Translational Psychiatry, 2022
Depression during and after pregnancy affects up to 20% of pregnant women, but the biological underpinnings remain incompletely understood. As pregnancy progresses, the immune system changes to facilitate fetal development, leading to distinct ...
Qiong Sha, Zach Madaj, Sarah Keaton, Martha L Escobar Galvis, LeAnn Smart, Stanislaw Krzyzanowski, Asgerally T. Fazleabas, Richard Leach, Teodor T. Postolache, Eric D. Achtyes, Lena Brundin   +10 more
doaj   +1 more source

Use of superheated liquids for the extraction of non-volatile compounds from wood: HPLC studies [PDF]

, 2004
A study of the extraction of oak wood compounds using superheated water-ethanol mixtures ranging from 10 to 60% ethanol is reported. Identification and characterization of the extracted compounds have been made by high performance liquid chromatography ...
Chatonnet, Cutzach, Cutzach, Delgado, Giménez Martı́nez, González-Rodrı́guez, J González-Rodrı́guez, M.D Luque de Castro, P Pérez-Juan, Sarni, Scalbert, Tricard, Viriot   +12 more
core   +1 more source

Solubility and Crystallization Studies of Picolinic Acid

Crystals, 2023
Solubility and crystallization studies of a monocarboxylic derivative of pyridine, picolinic acid (2-pyridinecarboxylic acid), were undertaken as a need for new data in the literature was identified. Moreover, comparative studies of structurally related small molecules, such as these pyridinecarboxylic acid isomers (picolinic acid (PA), nicotinic acid (
Diogo S. Baptista, M. Fátima M. Piedade, Catarina V. Esteves   +2 more
openaire   +2 more sources