Results 71 to 80 of about 5,045,142 (209)
New coordination polymers of cobalt(II), namely, [Co(μ4-cpna)(H2O)2] n (1), [Co(μ3-cpna)(phen)(H2O)] n· nH2O (2), [Co3(μ4-dppa)2(H2O)6] n·2 nH2O (3), and [Co3(μ5-dppa)2(μ-4,4'-bipy)(H2O)2] n·4 nH2O (4), have been generated under hydrothermal conditions ...
Jinzhong Gu +6 more
semanticscholar +1 more source
ABSTRACT Major depressive disorder (MDD) is a mood disorder that causes serious functional impairment. Existing diagnostic methods rely on subjective assessments because of its complex and heterogeneous pathophysiology; therefore, development of objective biomarkers is urgently needed.
Seungyeon Lee +5 more
wiley +1 more source
Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity [PDF]
The free fatty acid receptor 4 (FFA4 or GPR120) has appeared as an interesting potential target for the treatment of metabolic disorders. At present, most FFA4 ligands are carboxylic acids that are assumed to mimic the endogenous long-chain fatty acid ...
Azevedo, Carlos +11 more
core +3 more sources
Unique metabolic signatures are associated with both response and resistance to cancer immunotherapy. These signatures can be used to predict response to treatment and in the future, metabolites could potentially be used to enhance specific types of immune response associated with favourable immunological outcomes. Abstract Checkpoint inhibitor therapy
Agnieszka Beata Malczewski +3 more
wiley +1 more source
Mechanistic investigations of the asymmetric hydrosilylation of ketimines with trichlorosilane reveals a dual activation model and an organocatalyst with enhanced efficiency. [PDF]
Structural probes used to help elucidate mechanistic information of the organocatalyzed asymmetric ketimine hydrosilylation have revealed a new catalyst with unprecedented catalytic activity, maintaining adequate performance at 0.01 mol% loading.
A. T. Reeder +33 more
core +1 more source
The microbial pathways of tryptophan metabolism predominate in active snakes, while the 5‐hydroxytryptamine pathway and kynurenine pathway govern tryptophan catabolism in hibernating snakes. ABSTRACT Hibernation is a common behavioral strategy for snakes to cope with extreme environments.
Yuting Wei +10 more
wiley +1 more source
Metabolomics Revealed the Differential Metabolites of Different Broomcorn Millet Varieties in Shanxi
A total of 1119 metabolites were identified among different varieties of millet, including 16 major categories such as phenols, alkaloids, and phenylpropanoids. The main pathways of differences among different varieties of millet include tryptophan metabolism, purine metabolism, phenylalanine metabolism, etc. The grain color correlates with β‐carotene,
Chao Jiang +4 more
wiley +1 more source
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu +8 more
wiley +1 more source
Background Prolonged exposure to cold stress in cattle increases basal energy consumption and impedes optimal production. Consequently, herds require adequate attention during cold, extended winters to alleviate cold stress and maintain profitability ...
Yongliang Huang +7 more
doaj +1 more source

