Results 71 to 80 of about 5,118,399 (260)

Effects of Heat Exposure on Kynurenine Pathway Metabolism—Comparison Between Exertional and Exogenous Heating of the Human Body

Acta Physiologica, Volume 241, Issue 12, December 2025.
ABSTRACT Background The kynurenine pathway (KP) plays a pivotal role in many diseases that involve distinct pathological mechanisms. Objectives Since KP metabolites are potential disease biomarkers, it is crucial to investigate their fluctuations under physiological conditions.
Varvara Louvrou, Nerijus Eimantas, Ema Juškevičiūtė, Rima Solianik, Marius Brazaitis, Göran Engberg, Sophie Erhardt   +6 more
wiley   +1 more source

Electrochemical Synthesis of Nicotinic Acid from ��-Picoline

, 1988
Department of Chemistry, Kashmir University, Srinagar-190 006 Manuscript received 18 February 1988, revised 19 May 1988, accepted 8 June 1988 Electrosyathesis or nicotinic acid from -picoline by potentiostatic oxidation is reported. Efficencies of different electrodes are compared by considering changes in concentration of anolyte and substrate ...
P. N. GUPTA, G. M. RATHER
openaire   +1 more source

Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids.

Journal of the American Chemical Society, 2020
Fusaric acid (FA) is a well-known mycotoxin that plays an important role in plant pathology. The biosynthetic gene cluster for FA has been identified, but the biosynthetic pathway remains unclarified.
Y. Hai, Mengbing Chen, Arthur Huang, Yi Tang   +3 more
semanticscholar   +1 more source

Tryptophan derivatives as non‐invasive diagnostic indicators for obesity‐related MASLD in children and adolescents

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7544-7560, December 2025.
Abstract Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents a major health burden in children and adolescents with obesity. This study aimed to characterize metabolic alterations associated with obesity‐related MASLD and to evaluate the potential of tryptophan (TRP)‐derived metabolites as non‐invasive biomarkers for early ...
Shumin Zhan, Xingyun Wang, Chen Wang, Bowen Zhu, Jianfang Gao, Zhou Peng, Rui Wang, Yun Yang, Liang Zhang, Tengfei Wang, Jiaoxiang Wu, Wei Wu, Ke Huang, Guanping Dong, Qiannan Ren, Shan Wang, Senjie Wang, Xuelian Zhou, Liling Xu, Junfen Fu, Xirong Guo   +20 more
wiley   +1 more source

Mechanistic investigations of the asymmetric hydrosilylation of ketimines with trichlorosilane reveals a dual activation model and an organocatalyst with enhanced efficiency. [PDF]

, 2017
Structural probes used to help elucidate mechanistic information of the organocatalyzed asymmetric ketimine hydrosilylation have revealed a new catalyst with unprecedented catalytic activity, maintaining adequate performance at 0.01 mol% loading.
A. T. Reeder, Baudequin, Bonsignore, Braun, Cowley, El-Fayyoumy, F. Torri, Gautier, Gautier, Guizzetti, Guizzetti, H. Adams, Hagemann, Imamoto, Iwasaki, Jones, Jones, Malkov, Malkov, Malkov, Nakayama, Ngochindo, Onomura, Pei, Pei, S. Jones, Shirley, Sugiura, Wang, Warner, X. Li, Xiao, Zhang, Zheng   +33 more
core   +1 more source

Fe‐Photocatalyzed Decarboxylative Giese‐Type Reaction of α‐N, O or S Carboxylic Acids: Insight into the Mechanism of the Radical Formation

Advanced Synthesis &Catalysis, Volume 367, Issue 21, November 13, 2025.
Electron‐deficient alkenes can be functionalized with α‐amino, α‐alkoxy and α‐alkylthio radicals formed by Fe‐photocatalyzed decarboxylation of the corresponding carboxylic acids. The reactions proceed under smooth ligandless conditions with inexpensive base and in the absence of oxidant. A mechanistic computational TD‐DFT study supports the occurrence
Fernando Pérez‐Maseda, María Martín, Jorge Labrador‐Santiago, Inés Corral, Diego J. Cárdenas   +4 more
wiley   +1 more source

Design, Synthesis, Herbicidal Activity, and Structure–Activity Relationship Study of Novel 6-(5-Aryl-Substituted-1-Pyrazolyl)-2-Picolinic Acid as Potential Herbicides [PDF]

, 2023
Tong Feng, Qing Liu, Zhiyuan Xu, Huiting Li, Wei Wei, Rong-Chuan Shi, Li Zhang, Yiming Cao, Shangzhong Liu   +8 more
openalex   +1 more source

Cobalt(II) Coordination Polymers Assembled from Unexplored Pyridine-Carboxylic Acids: Structural Diversity and Catalytic Oxidation of Alcohols.

Inorganic Chemistry, 2019
New coordination polymers of cobalt(II), namely, [Co(μ4-cpna)(H2O)2] n (1), [Co(μ3-cpna)(phen)(H2O)] n· nH2O (2), [Co3(μ4-dppa)2(H2O)6] n·2 nH2O (3), and [Co3(μ5-dppa)2(μ-4,4'-bipy)(H2O)2] n·4 nH2O (4), have been generated under hydrothermal conditions ...
Jinzhong Gu, Min Wen, Yan Cai, Zifa Shi, Dmytro S. Nesterov, M. Kirillova, A. Kirillov   +6 more
semanticscholar   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Picolinic Acid, a Catabolite of Tryptophan, Has an Anabolic Effect on Bone In Vivo [PDF]

, 2020
Gustavo Duque, Christopher Vidal, Wei Li, Ahmed Al Saedi, Mamdouh Khalil, Chai K. Lim, Damian E. Myers, Gilles J. Guillemin   +7 more
openalex   +1 more source