Results 31 to 40 of about 35,784 (230)

Mechanism, Formulation, and Efficacy Evaluation of Natural Products for Skin Pigmentation Treatment

open access: yesPharmaceutics
Skin pigmentation typically arises from the excessive secretion and accumulation of melanin, resulting in a darker complexion compared to normal skin. Currently, the local application of chemical drugs is a first-line strategy for pigmentation disorders,
Xueli Peng   +9 more
doaj   +1 more source

Focal Scalp Hair Heterochromia in an Infant

open access: yesSultan Qaboos University Medical Journal, 2017
Hair heterochromia involves the presence of two different non-artificially induced colours of hair in the same individual which can be due to either iron deficiency anaemia, genetic mutations or mosaicism.
Pramod Kumar
doaj   +1 more source

Shining Light on Autophagy in Skin Pigmentation and Pigmentary Disorders

open access: yesCells, 2022
Autophagy is a vital process for cell survival and it preserves homeostasis by recycling or disassembling unnecessary or dysfunctional cellular constituents.
Daniela Kovacs   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Dabigatran‐induced esophagitis with full circumferential blue pigmentation

open access: yesDEN Open
Dabigatran is a useful and widely used drug for stroke prevention in patients with atrial fibrillation. However, it has been reported to cause esophagitis.
Tomonori Araki   +7 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Disorders of pigmentation: unapproved treatments

open access: yesClinics in Dermatology, 2002
Aprescription is considered unapproved when the condition being treated is not listed on the package insert or in the Physician’s Desk Reference as an indication for the drug being used. There is a perception among some that if a therapy were truly effective and safe for a particular indication, it would have received official Food and Drug ...
Katsambas, A, Stefanaki, C
openaire   +3 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

open access: yesAdvanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes   +4 more
wiley   +1 more source

A Woman with Treated Breast Cancer, Recent Neurological Symptoms and Xanthoderma

open access: yesActa Medica Iranica, 2013
We describe a 69-year-old-woman with antecedent of breast cancer and recent transitory neurological symptoms. Physical examination showed yellow to orange skin pigmentation, more conspicuous on her palms and soles, while discoloration changes were absent
Vitorino Modesto dos Santos   +5 more
doaj   +2 more sources

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