Results 21 to 30 of about 19,713 (201)

Functionally different PIN proteins control auxin flux during bulbil development in Agave tequilana [PDF]

open access: yes, 2015
In Agave tequilana, reproductive failure or inadequate flower development stimulates the formation of vegetative bulbils at the bracteoles, ensuring survival in a hostile environment.
Abraham Juarez, Maria Jazmin   +8 more
core   +2 more sources

Hyperglycemia induces gastric carcinoma proliferation and migration via the Pin1/BRD4 pathway

open access: yesCell Death Discovery, 2022
Diabetes is a potential risk factor for gastric cancer (GC). Pin1, a peptidyl–prolyl cis/trans isomerase, promotes GC cell proliferation and migration.
Jianjian Yu   +8 more
doaj   +1 more source

Endocytic signaling in leaves and roots: same rules different players. [PDF]

open access: yes, 2012
To take up proteins and other components required by the cell, cells internalize a portion of the plasma membrane (PM), which invaginates to form a closed vesicle within the cytoplasm in a process known as endocytosis. The major plant endocytic mechanism
Craddock, Christian, Yang, Zhenbiao
core   +2 more sources

Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16

open access: yesCell Reports, 2019
Summary: Non-shivering thermogenesis in adipocytes provides defense against low temperatures and obesity development, but the underlying regulatory mechanism remains to be fully clarified.
Yusuke Nakatsu   +24 more
doaj   +1 more source

Prolyl isomerase Pin1 in cancer [PDF]

open access: yesCell Research, 2014
Proline-directed phosphorylation is a posttranslational modification that is instrumental in regulating signaling from the plasma membrane to the nucleus, and its dysregulation contributes to cancer development. Protein interacting with never in mitosis A1 (Pin1), which is overexpressed in many types of cancer, isomerizes specific phosphorylated Ser ...
Zhimin, Lu, Tony, Hunter
openaire   +2 more sources

The transcription factors BEL1 and SPL are required for cytokinin and auxin signaling during ovule development in Arabidopsis [PDF]

open access: yes, 2012
Hormones, such as auxin and cytokinin, are involved in the complex molecular network that regulates the coordinated development of plant organs. Genes controlling ovule patterning have been identified and studied in detail; however, the roles of auxin ...
Bencivenga, Stefano   +3 more
core   +3 more sources

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease

open access: yesNeurobiology of Disease, 2015
The unique proline isomerase Pin1 is pivotal for protecting against age-dependent neurodegeneration in Alzheimer's disease (AD), with its inhibition providing a molecular link between tangle and plaque pathologies.
Chun-Hau Chen   +16 more
doaj   +1 more source

Serum peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 in combination with C-reactive protein and white blood cell as novel predictors for infants with community-acquired pneumonia

open access: yesEuropean Journal of Inflammation, 2020
The aim of this study was to investigate the predictive value of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with C-reactive protein (CRP) and white blood cell (WBC) count for community-acquired pneumonia (CAP) in infants. A total of 84
Heng Xue   +8 more
doaj   +1 more source

Peptidyl-prolyl cis/trans isomerase Pin1 interacts with hepatitis B virus core particle, but not with HBc protein, to promote HBV replication

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Here, we demonstrate that the peptidyl-prolyl cis/trans isomerase Pin1 interacts noncovalently with the hepatitis B virus (HBV) core particle through phosphorylated serine/threonine-proline (pS/TP) motifs in the carboxyl-terminal domain (CTD) but not ...
Hyeonjoong Kwon   +17 more
doaj   +1 more source

PIN1-Independent Leaf Initiation in Arabidopsis     [PDF]

open access: yesPlant Physiology, 2012
AbstractPhyllotaxis, the regular arrangement of leaves and flowers around the stem, is a key feature of plant architecture. Current models propose that the spatiotemporal regulation of organ initiation is controlled by a positive feedback loop between the plant hormone auxin and its efflux carrier PIN-FORMED1 (PIN1).
Guenot, B   +7 more
openaire   +4 more sources

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