Results 111 to 120 of about 23,348 (143)
Efficacy of pioglitazone in treatment of metabolic dysfunction-associated fatty liver disease
Background and aim Nonalcoholic fatty liver disease has emerged as a major public health challenge, with limited approved pharmacological therapies.
Mahmoud M. Khafagi +5 more
doaj +1 more source
Redox-dependent gating of VDAC by mitoNEET. [PDF]
MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson's ...
Bai, Fang +8 more
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Masahiro Ohira,1 Takashi Yamaguchi,1 Atsuhito Saiki,1 Noriko Ban,1 Hidetoshi Kawana,1 Ayako Nagumo,1 Takeyoshi Murano,2 Kohji Shirai,3 Ichiro Tatsuno1 1Center for Diabetes, Endocrinology and Metabolism, 2Department of Clinical Laboratory Medicine ...
Ohira M +8 more
doaj
Pharmacokinetic interactions of pioglitazone [PDF]
Pioglitazone is a thiazolidinedione compound used in the treatment of type 2 diabetes. It has been reported to be metabolised by multiple cytochrome P450 (CYP) enzymes, including CYP2C8, CYP2C9 and CYP3A4 in vitro.
Jaakkola, Tiina
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Risk management in the treatment of type 2 diabetes with pioglitazone
Giuseppe Derosa, Sibilla AT SalvadeoDepartment of Internal Medicine and Therapeutics, University of Pavia, Pavia, ItalyIntroduction: Type 2 diabetes mellitus is one of the most important cardiovascular risk factors.
Giuseppe Derosa, Sibilla AT Salvadeo
doaj
Background Pioglitazone significantly reduces the risk of stroke in people with diabetes, and in those with prediabetes, it markedly reduces the risk of stroke/myocardial infarction and new‐onset diabetes.
Fei Yuan +2 more
doaj +1 more source
Do TZDs increase the risk of heart failure for patients with diabetes? [PDF]
Patients with diabetes who take thiazolidinediones (TZDs) have a higher incidence of congestive heart failure (CHF) than those who do not; the incidence of CHF is similar with the use of pioglitazone (Actos), troglitazone (Rezulin), or rosiglitazone ...
Baskin, Serena +2 more
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Nasser MikhailEndocrinology Division, Olive View-UCLA Medical Center, David-Geffen School of Medicine, CA, USAAbstract: Sitagliptin and vildagliptin represent a new class of anti-diabetic agents that enhance the action of incretin hormones through ...
Nasser Mikhail
doaj
Nebulized PPARγ agonists: a novel approach to augment neonatal lung maturation and injury repair in rats. [PDF]
BackgroundBy stimulating lipofibroblast maturation, parenterally administered peroxisome proliferator-activated receptor γ (PPARγ) agonists promote lung homeostasis and injury repair in the neonatal lung.
Gong, Ming +9 more
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