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Synthesis of Pipecolic Acid and Baikiain.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Meng-Yang Chang +2 more
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Epoxide derivatives of pipecolic acid and proline are inhibitors of pipecolate oxidase
Bioorganic & Medicinal Chemistry Letters, 1998The cis-4,5-epoxide derivative of L-pipecolic acid (2S,4S,5R-epoxypipecolic acid, cis-3) was synthesized and found to serve as an excellent substrate for L-pipecolate oxidase (L-PO) and also to cause time-dependent, irreversible inactivation of the enzyme. Data are presented showing this compound is a mechanism-based inhibitor of L-PO, whereas 2S,3R,4S-
B, Ho, T M, Zabriskie
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Biotechnology and Bioprocess Engineering, 2019 Pipecolic acid is an unnatural amino acid mostly used for pharmaceutical purposes. Pipecolic acid has two types of enantiomers with different roles in the synthesis of drugs.
Jeong Chan Joo +2 more
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An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids
Tetrahedron: Asymmetry, 2005Both (R)- and (S)-pipecolic acids and their 2-alkyl derivatives have been synthesized via diastereoselective alkylations of (R)-5-phenylmorpholin-2-one 5.
Duen-Ren Hou +2 more
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The oxidation of pipecolic acid in preincubated soils
Folia Microbiologica, 1970Chernozem soil was preincubated with 0.1% glucose, glucose plus ammonium nitrate, hydrolyzed casein or amino acids for five days and with 1% wheat straw, pectin, peptone or cellulose for ten days. The soil was modified by this treatment so that the pipecolic acid was oxidized in two steps, as was shown by two peaks on the graphic plot of the oxygen ...
M A, Guirguis, V, Vancura
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Recent advances in asymmetric synthesis of pipecolic acid and derivatives
Amino Acids, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sébastien Comesse
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Enantioanalysis of Pipecolic Acid with Stochastic and Potentiometric Microsensors
Chirality, 2012ABSTRACTStochastic and potentiometric microsensors based on porphyrins and polymeric surfactants such as polysodium N‐undecanoyl‐ l‐leucylvanilate and polysodium N‐undecanoyl‐ l‐vanilate were developed for enantioselective assay of pipecolic acid. The matrices used for the design of the stochastic sensors were diamond paste and graphite paste, while ...
Stefan‐van Staden, Raluca‐Ioana +9 more
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Synthetic application of pipecolic acid
Research on Chemical Intermediates, 2014Pipecolic acid is used as organocatalyst and novel substrate in organic synthesis. Organocatalysis-based methodologies for asymmetric transformations are now the frontier field of research in chiral synthesis. In the recent years, pipecolic acid opens a new avenue as an organocatalyst and as an important substrate in various reactions.
Seetaram Mohapatra +3 more
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Biosynthesis of pipecolic acid and 4-hydroxypipecolic acid
Phytochemistry, 1986Abstract Pipecolic acid is formed from lysine, and 4-hydroxypipecolic acid is formed from pipecolic acid in the leaves of Acacia mellifera subsp. detinens .
J.J.Marion Meyer, Nathanaël Grobbelaar
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The determination of pipecolic acid in serum and urine
Clinica Chimica Acta, 1972Abstract A method is described for the determination of the imino acid, pipecolic acid in serum and urine. Serum is deproteinised with absolute ethanol and urine is desalted by ion exchange chromatography. Pipecolic acid is partially separated from amimo acids present in serum and urine by ascending paper chromatography.
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