Results 101 to 110 of about 13,032 (188)
CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.MCC‐135 treatment significantly prolonged the seizure latency and alleviated hippocampal neuronal damage in KA‐induced epileptic mice. Furthermore, MCC‐135 reduced NCX1 levels, alleviated intracellular calcium overload, and downregulated glutamate levels in the epileptic mice.
Chaoning Liu +10 more
wiley +1 more source
Macromolecular Chemistry and Physics, Volume 227, Issue 5, 13 March 2026.Cationic poly(2‐oxazoline)s (POx) have emerged as versatile materials for different biomedical applications. The combination of the pseudo‐peptidic polymer backbone and the amine‐derived cationic motifs results in well‐tolerated polymers with potential benefits for drug and gene delivery as well as antimicrobial development.
Meike N. Leiske
wiley +1 more source
Journal of Peptide Science, Volume 32, Issue 3, March 2026.Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss +8 more
wiley +1 more source
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Against the backdrop of global clean energy transition and surging demand for lithium resources, lithium extraction from salt lakes presents unprecedented development opportunities. Nanofiltration (NF) membrane technology, recognized for its efficiency, energy savings, and environmental benefits, demonstrates significant application potential ...
Wen‐Feng Li +5 more
wiley +1 more source
Copper‐Catalyzed Three‐Component Selective 1,4‐Amino Oxygenation of 1,3‐Dienes
Angewandte Chemie, Volume 138, Issue 8, 16 February 2026.Enclosed is a copper‐catalyzed selective 1,4‐amino oxgenation of 1,3‐dienes with the presence of a strong Brønsted acid. This three‐component transformation offers a novel and powerful approach to construct (E)‐1,4‐allylic amino oxygenated motifs by the simultaneous installation of structurally diverse alkylamines and alcohols directly onto 1,3‐dienes.
Guangshou Feng +2 more
wiley +2 more sources
Small Science, Volume 6, Issue 3, March 2026.This study examines how the physico‐chemical properties of gold nanorods (AuNR) influence their interactions with human immune cells. Antibody‐targeted AuNR selectively bind and induce apoptosis in T‐lymphocytes during photothermal therapy. In contrast, neutrophils have a high intrinsic phagocytic capacity and the design of selective particles requires
Tista Roy Chaudhuri +12 more
wiley +1 more source
Beilstein Journal of Organic ChemistryPiperazines and diazepines are examples of nitrogen heterocycles present in many marketed drugs highlighting their importance in the discovery of novel bioactive compounds.
Javier Gómez-Ayuso +5 more
doaj +1 more source
Drug Product Development of Lipid Nanoparticle‐Based mRNA Therapeutics and Vaccines
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.Overview of the development path from an mRNA–lipid nanoparticle (LNP) concept to a licensed drug product, covering LNP design, manufacturing process development, formulation, and analytical characterization. ABSTRACT Lipid nanoparticles (LNP) are currently the most relevant non‐viral delivery systems for mRNA and occasionally for smaller nucleic acids
Gideon Kersten +4 more
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1564-1577, March 2026.ABSTRACT Iron (Fe) is an essential micronutrient for plant growth and development. Rhizosphere microorganisms play crucial roles in plant Fe nutrition, yet the underlying mechanisms remain largely unknown. Here, we assessed the effect of the volatile organic compounds (VOCs) produced by Bacillus velezensis SQR9 on Fe uptake in Arabidopsis, elucidated ...
Taimeng Tan +12 more
wiley +1 more source
Safety assessment of poly(2‐ethyl‐2‐oxazoline) for use in food contact materials
EFSA Journal, Volume 24, Issue 3, March 2026.Abstract The EFSA Panel on Food Contact Materials (FCM) assessed the safety of poly(2‐ethyl‐2‐oxazoline) intended to be used as an additive to manufacture repeated use filter membranes based on ■■■■■. The filter membranes are used to process aqueous and alcoholic foods, for up to 24 h per day up to ■■■■■ at temperatures up to 35°C.
EFSA Panel on Food Contact Materials (FCM) +18 more
wiley +1 more source