Results 91 to 100 of about 39,960 (300)
Molecules, 2020 We reported a novel simplified synthetic procedure for the preparation of monosubstituted piperazine derivatives which can now be easily prepared in a one-pot-one-step way from a protonated piperazine with no need of introduction of a protecting group ...
Dana Němečková +4 more
doaj +1 more source
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
Radiation mitigation of the intestinal acute radiation injury in mice by 1-[(4-nitrophenyl)sulfonyl]-4-phenylpiperazine. [PDF]
, 2020 The objective of the study was to identify the mechanism of action for a radiation mitigator of the gastrointestinal (GI) acute radiation syndrome (ARS), identified in an unbiased high-throughput screen.
Alli, Claudia +11 more
core +1 more source
Iridium- and Ruthenium-Catalyzed N-alkylation of Amines with Alcohols and Amines [PDF]
, 2012 Mange biologisk aktive molekyler indeholder et eller flere nitrogen atomer. Derfor er dannelse af C-N bindinger et yderst vigtigt felt indenfor udvikling af medicin.
Lorentz-Petersen, Linda Luise Reeh
core
Synthesis of 6- and 7-Membered N-Heterocycles Using α-Phenylvinylsulfonium Salts [PDF]
, 2015 A concise synthesis of stereodefined C-substituted morpholines, piperazines, azepines, and oxazepines in moderate to excellent yields (27% to 75%) is reported by reaction of 1,2- or 1,3-amino alcohol/1,2- or 1,3-diamine with an α-phenylvinylsulfonium ...
Eoghan M. McGarrigle +7 more
core +2 more sources
Arthritis &Rheumatology, EarlyView.Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis +9 more
wiley +1 more source
The challenge of synthetic drugs in East and South-East Asia and Oceania [PDF]
The demand for synthetic drugs in East and Southeast Asia and Oceania continues to rise, while rapid economic integration is creating new opportunities for transnational criminal groups to expand the illicit drug trade, warns the United Nations Office on
Justice Tettey
core
Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of attention deficit hyperactivity disorder [PDF]
, 2015 Attention deficit hyperactivity disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also
Dwoskin, Linda P. +2 more
core +1 more source
Defect engineering for highly efficient and stable perovskite top cells for Si tandems
Bulletin of the Korean Chemical Society, EarlyView.Defect passivation in wide‐bandgap perovskites is essential for enabling high‐efficiency and stable perovskite/Si tandem solar cells. Bulk, surface, and buried‐interface passivation strategies focus on suppressing nonradiative recombination, ion migration, and halide segregation, thereby clarifying critical design principles for next‐generation tandem ...
Ju Yeong Hong +2 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Comparison of PSA and amine‐based absorption for syngas purification shows that PSA offers lower energy intensity, global warming potential, and minimum selling price, making it a more sustainable option. However, absorption achieves higher syngas purity. A GREENSCOPE‐based multi‐criteria assessment guides optimal process selection.
Magno Fonseca Santos +2 more
wiley +1 more source