Results 71 to 80 of about 15,176 (256)

Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones

, 2016
Silicon amine protocol (SLAP) reagents for photocatalytic cross-coupling with aldehydes and ketones to form N-unprotected piperazines have been developed.
Bode, Jeffrey W., Sheng-Ying Hsieh, Jeffrey W. Bode (1331538), Sheng-Ying Hsieh (1331529), Jeffrey W. Bode, Hsieh, Sheng-Ying, Hsieh SY, Bode JW   +7 more
core   +2 more sources

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some Novel Substituted Piperazinyl-quinazolin-3(4H)-ones

E-Journal of Chemistry, 2008
Several substituted-quinazolin-3(4H)-ones were synthesized by condensation of 2-chloro-N-(4-oxo-substituted-quinazolin-3(4H)-yl)-acetamides with various substituted piperazines through single step reaction. Elemental analysis, IR, 1HNMR and mass spectral
N. M. Raghavendra, P. P. Thampi, P. M. Gurubasavarajaswamy   +2 more
doaj   +1 more source

Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization

Advanced Science, EarlyView.
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang, Zhisen Zhang, Yuanyu Zhou, Wenzhi Wu, Congrui Zhao, Chang Liu, Tong Shi, Wenjing Jin, Zhaoming Liu, Weifeng Fang, Qingyun Lin, Yi He, Zhijian Xie, Ruikang Tang, Changyu Shao, Zhuo Chen   +15 more
wiley   +1 more source

Designer drugs: aspectos analíticos e biológicos

Química Nova, 2012
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão, Solange Cristina Garcia, Renata Pereira Limberger, Marília Baierle, Marcelo Dutra Arbo, Alice Aparecida da Matta Chasin, Flávia Valladão Thiesen, Rejane Tavares   +7 more
doaj   +1 more source

Toward Rational Design of Aqueous Battery Membranes Beyond the Selectivity‐Conductivity Trade‐Off

Advanced Science, EarlyView.
This review examines sulfonated membranes for redox flow batteries. It focuses on proton transport mechanism, membrane design, performance limits, optimization strategies, and the pathway from molecular design to membrane manufacturing. ABSTRACT Electrochemical energy‐storage systems increasingly require membranes that can simultaneously deliver fast ...
Jinkang Liu, Mingbo Xie, Zhenghao Wang, Huacun Li, Jun Xie, Pan Liu, Qingwei Wang, Xu Yan, Meiqing Shi, Liyuan Chai, Yue Luo, Zining Tang, Rui Tan, Liyuan Zhang   +13 more
wiley   +1 more source

Chemical Rounding Suppresses Morphology‐Induced Interfacial Losses in Perovskite–Silicon Tandem Solar Cells

Advanced Energy Materials, EarlyView.
Chemical rounding transforms irregular submicron silicon textures into more favorable interfaces for perovskite–silicon tandems. Suppressed local epitaxial ordering improves bottom‐cell passivation, while the top‐cell stack exhibits a higher and more spatially uniform quasi‐Fermi‐level splitting, enabling monolithic tandem solar cells with an ...
Nan Sun, Binbin Xu, Gaosheng Huang, Yuehui Li, Karsten Bittkau, Eunseo Noh, Sercan Aslan, Andreas Lambertz, Sang Il Seok, Michael Saliba, Christoph J. Brabec, Thomas Kirchartz, Kaining Ding   +12 more
wiley   +1 more source

Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted ...
Andrea Angeli, Niccolò Chiaramonte, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran   +4 more
doaj   +1 more source

Iridium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes with N-Substituted Piperazine Nucleophiles

Molecules, 2015
Iridium-catalyzed asymmetric ring-opening of oxabenzonorbornadienes with N-substituted piperazines was described. The reaction afforded the corresponding ring-opening products in high yields and moderate enantioselectivities in the presence of 2.5 mol % [
Wen Yang, Renshi Luo, Dingqiao Yang
doaj   +1 more source

Direct synthesis of piperazines containing dithiocarbamate derivatives via DABCO bond cleavage

, 2020
DABCO bond cleavage with dithiocarbamic acid salts was applied as a direct synthetic route for the preparation of a novel category of piperazines containing dithiocarbamate functional group.
Soleymani, F., Asar, F.J., Hooshmand, S.E., Halimehjani, A.Z.   +3 more
core